AQR and PQBP1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		AQR	PQBP1
Gene Name		aquarius intron-binding spliceosomal factor	polyglutamine binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule
	Molecular Function	Protein Binding Poly(A) RNA Binding	DNA Binding Transcription Coactivator Activity Ribonucleoprotein Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Neuron Projection Development Regulation Of RNA Splicing Regulation Of Dendrite Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: PQBP1 RBM22 RBM4 WDR77 WDR83	23 interactors: APBB1 APP AQR ATXN1 C14orf1 CLTB EEF1A1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77
Entrez ID		9716	10084
HPRD ID		12468	02354
Ensembl ID		ENSG00000021776	ENSG00000102103
Uniprot IDs		O60306	O60828
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Nitrogen Compound Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development IRES-dependent Translational Initiation Cap-independent Translational Initiation Circadian Regulation Of Translation Negative Regulation Of Translation In Response To Stress Ribonucleoprotein Complex Biogenesis Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Cytoplasmic Translational Initiation Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Alternative MRNA Splicing, Via Spliceosome Regulation Of Intracellular Transport Cytoplasmic Translation Stress Granule Assembly Regulation Of Translation In Response To Stress MRNA Cis Splicing, Via Spliceosome Epithelial Cell Differentiation Involved In Prostate Gland Development Negative Regulation Of Translational Initiation Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Entrainment Of Circadian Clock By Photoperiod Regulation Of RNA Metabolic Process Photoperiodism Entrainment Of Circadian Clock Response To Arsenic-containing Substance Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Into Nucleus, Translocation Cellular Macromolecular Complex Assembly Positive Regulation Of RNA Splicing Gene Silencing By MiRNA Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Posttranscriptional Gene Silencing Spliceosomal SnRNP Assembly Glandular Epithelial Cell Differentiation Cellular Response To Drug Gene Silencing By RNA	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Visual Learning Visual Behavior Associative Learning Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Response To Light Stimulus Learning Regulation Of Protein Binding Nitrogen Compound Metabolic Process Mitotic Cell Cycle Cell Division Response To Radiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Respiratory Gaseous Exchange Cell Cycle Regulation Of Neuron Differentiation Regulation Of Binding Learning Or Memory Neurohypophysis Development Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated Cell Cycle Process Negative Regulation Of Neurogenesis Cognition Positive Regulation Of Microtubule Plus-end Binding Collateral Sprouting In Absence Of Injury Golgi Vesicle Fusion To Target Membrane Regulation Of Nitrogen Compound Metabolic Process Mitotic Nuclear Division Response To Abiotic Stimulus Positive Regulation Of Cellular Biosynthetic Process Ribonucleoprotein Complex Biogenesis Mitotic Cell Cycle Process Neuron Differentiation Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Development Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		adaptor adf afd arr arrestin asi balanced caenorhabditis chemosensory consequences deleterious elegans excessive gpcr gpcrs homeostasis immunity innate insufficient killing longevity microbial organismal pathogen played pqr thermosensory unfolded urx	amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Difference) ?		adaptor adf afd arr arrestin asi balanced caenorhabditis chemosensory consequences deleterious elegans excessive gpcr gpcrs homeostasis immunity innate insufficient killing longevity microbial organismal pathogen played pqr thermosensory unfolded urx	amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Intersection) ?