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RBM4 and PABPC1
Number of citations of the paper that reports this interaction (PubMedID
22365833
)
0
Data Source:
BioGRID
(two hybrid)
RBM4
PABPC1
Description
RNA binding motif protein 4
poly(A) binding protein cytoplasmic 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Perinuclear Region Of Cytoplasm
Nucleus
Spliceosomal Complex
Cytoplasm
Cytosol
Focal Adhesion
Cytoplasmic Stress Granule
Membrane
Lamellipodium
Cell Leading Edge
Cytoplasmic Ribonucleoprotein Granule
Cell Projection
Extracellular Exosome
Catalytic Step 2 Spliceosome
MCRD-mediated MRNA Stability Complex
Ribonucleoprotein Complex
Molecular Function
Nucleic Acid Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Zinc Ion Binding
Cyclin Binding
MiRNA Binding
Pre-mRNA Binding
Metal Ion Binding
Pre-mRNA Intronic Binding
Pre-mRNA Intronic Pyrimidine-rich Binding
Nucleic Acid Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
Translation Activator Activity
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Cap-independent Translational Initiation
IRES-dependent Translational Initiation Of Linear MRNA
RNA Processing
MRNA Processing
Circadian Rhythm
RNA Splicing
Regulation Of Gene Expression
Negative Regulation Of Translation
Cell Differentiation
Pancreas Development
Regulatory NcRNA-mediated Gene Silencing
Negative Regulation Of Translation In Response To Stress
Circadian Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Enteroendocrine Cell Differentiation
Glucose Homeostasis
Entrainment Of Circadian Clock By Photoperiod
Positive Regulation Of Translation
Negative Regulation Of Translational Initiation
Regulation Of Insulin Receptor Signaling Pathway
Response To Arsenic-containing Substance
Regulation Of Nucleocytoplasmic Transport
Positive Regulation Of Muscle Cell Differentiation
Circadian Regulation Of Translation
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Regulatory NcRNA-mediated Gene Silencing
Positive Regulation Of Viral Genome Replication
MRNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
CRD-mediated MRNA Stabilization
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Positive Regulation Of Cytoplasmic Translation
Pathways
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
L13a-mediated translational silencing of Ceruloplasmin expression
Deadenylation of mRNA
Deadenylation of mRNA
AUF1 (hnRNP D0) binds and destabilizes mRNA
Translation initiation complex formation
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
M-decay: degradation of maternal mRNAs by maternally stored factors
Z-decay: degradation of maternal mRNAs by zygotically expressed factors
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Body mass index (
26426971
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
97 interacting genes:
AQR
CCNA1
CDK2
DDX17
DDX5
DHX9
ESS2
HNRNPF
HNRNPH2
HNRNPH3
HNRNPK
HNRNPM
HNRNPUL1
KLHL41
LRP2BP
MAPK8IP2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR10B
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15B
MIR16-2
MIR17
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PABPC1
PRPF31
PTBP2
PTEN
RBM10
RBM22
RBM23
RBM42
RBM7
RNF10
SF1
SF3B4
SMAD5
SNRPC
STEEP1
SURF6
TRIB3
U2AF2
55 interacting genes:
ANAPC5
APBB1
ATXN2
CARM1
CEBPA
CHAF1A
CNOT6
CNOT7
CSDE1
DUX4
EIF4B
EIF4G1
EIF4G3
ERBB2
GSPT1
GSPT2
HBB
HNRNPD
HNRNPK
IL7R
ITCH
LARP4B
LINC01554
MAPKAPK2
MKRN1
NDRG1
OGT
PAIP1
PAIP2
PAIP2B
PAN2
PAN3
PCBP1
PCBP2
PCSK7
PIN1
PRMT6
PXN
RACK1
RBM4
SNCA
SREK1
STAU1
SYCP3
SYNCRIP
TERT
TOB1
TOB2
U2AF1
UNK
USP10
USP7
WBP4
WEE2-AS1
YWHAG
Entrez ID
5936
26986
HPRD ID
03982
05247
Ensembl ID
ENSG00000173933
ENSG00000070756
Uniprot IDs
Q9BWF3
P11940
PDB IDs
2DNQ
1CVJ
1G9L
1JGN
1JH4
2K8G
2RQG
2RQH
2X04
3KTP
3KTR
3KUI
3KUJ
3KUR
3KUS
3KUT
3PKN
3PTH
4F02
4F25
4F26
5DX1
5DX8
5DXA
5LGP
5LGQ
5LGR
5LGS
7BN3
8SMO
Enriched GO Terms of Interacting Partners
?
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Gene Expression
Extracellular Vesicle
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of MRNA Metabolic Process
Negative Regulation Of Translation
Positive Regulation Of MRNA Catabolic Process
MRNA Destabilization
RNA Destabilization
Negative Regulation Of Cell Migration
Regulation Of Metabolic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Motility
Negative Regulation Of Vasculature Development
Regulation Of MRNA Stability
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Locomotion
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Regulation Of RNA Stability
Negative Regulation Of Cytokine Production
Regulation Of Translation
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Protein Metabolic Process
Regulation Of Endothelial Cell Migration
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Developmental Process
Regulation Of Cell Migration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Endothelial Cell Migration
MRNA Splicing, Via Spliceosome
Negative Regulation Of Signal Transduction
RNA Splicing, Via Transesterification Reactions
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Cell Motility
Post-transcriptional Regulation Of Gene Expression
Regulation Of Translation
RNA Binding
Regulation Of Protein Metabolic Process
Regulation Of Translational Initiation
Positive Regulation Of Translation
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Catabolic Process
Regulation Of MRNA Stability
Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of MRNA Metabolic Process
Regulation Of RNA Stability
Negative Regulation Of Metabolic Process
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
MCRD-mediated MRNA Stability Complex
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Translation
MRNA Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Cytosol
Nucleic Acid Binding
Nucleic Acid Metabolic Process
Negative Regulation Of Protein Metabolic Process
MRNA Metabolic Process
Regulation Of Biological Quality
Cytoplasmic Stress Granule
CRD-mediated MRNA Stabilization
RNA Metabolic Process
Poly(A)-specific Ribonuclease Activity
Positive Regulation Of Metabolic Process
Negative Regulation Of MRNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Cytoplasmic Translation
Positive Regulation Of Biosynthetic Process
MRNA Catabolic Process
Negative Regulation Of MRNA Catabolic Process
Positive Regulation Of Cytoplasmic Translation
RNA Catabolic Process
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Negative Regulation Of Translational Initiation
Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly
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