RBM4 and RBM7

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM4	RBM7
Description		RNA binding motif protein 4	RNA binding motif protein 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Cyclin Binding MiRNA Binding Pre-mRNA Binding Metal Ion Binding Pre-mRNA Intronic Binding Pre-mRNA Intronic Pyrimidine-rich Binding	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding SnRNA Binding 14-3-3 Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Cap-independent Translational Initiation IRES-dependent Translational Initiation Of Linear MRNA RNA Processing MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Gene Expression Negative Regulation Of Translation Cell Differentiation Pancreas Development Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Translation In Response To Stress Circadian Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Enteroendocrine Cell Differentiation Glucose Homeostasis Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Translation Negative Regulation Of Translational Initiation Regulation Of Insulin Receptor Signaling Pathway Response To Arsenic-containing Substance Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Muscle Cell Differentiation Circadian Regulation Of Translation	Regulation Of Alternative MRNA Splicing, Via Spliceosome SnRNA Catabolic Process Meiotic Cell Cycle
Pathways		Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	mRNA Splicing - Major Pathway Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Nuclear RNA decay
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		97 interacting genes: AQR CCNA1 CDK2 DDX17 DDX5 DHX9 ESS2 HNRNPF HNRNPH2 HNRNPH3 HNRNPK HNRNPM HNRNPUL1 KLHL41 LRP2BP MAPK8IP2 MIR1-1 MIR1-2 MIR106A MIR106B MIR10B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR17 MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PABPC1 PRPF31 PTBP2 PTEN RBM10 RBM22 RBM23 RBM42 RBM7 RNF10 SF1 SF3B4 SMAD5 SNRPC STEEP1 SURF6 TRIB3 U2AF2	27 interacting genes: APOBEC3C BAG4 CCDC85B CCDC88B CHERP CPSF7 DDX17 DHX8 DMRTB1 EVI5L EXOSC7 EXOSC8 HMG20A HNRNPK KHDRBS1 KHDRBS3 KRT31 QKI RBM10 RBM4 RBMX RBPMS SF1 SF3B2 SNRPA SRSF3 TFIP11
Entrez ID		5936	10179
HPRD ID		03982	11488
Ensembl ID		ENSG00000173933	ENSG00000076053
Uniprot IDs		Q9BWF3	G3V1T9 J3KPD3 Q9Y580
PDB IDs		2DNQ	2M8H 5IQQ 5LXR 5LXY 7S7B 7S7C
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Cell Migration Regulation Of Metabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Cell Motility Negative Regulation Of Vasculature Development Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Cytokine Production Regulation Of Translation Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration MRNA Splicing, Via Spliceosome Negative Regulation Of Signal Transduction RNA Splicing, Via Transesterification Reactions Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Cell Motility	RNA Processing MRNA Metabolic Process MRNA Processing Nucleic Acid Binding RNA Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Binding RNA Metabolic Process RNA Splicing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Catalytic Step 2 Spliceosome Nucleoplasm Negative Regulation Of MRNA Metabolic Process Nucleus Negative Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Splicing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasmic Stress Granule Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process MiRNA Binding Exoribonuclease Complex Negative Regulation Of RNA Metabolic Process Identical Protein Binding Regulation Of Gene Expression Negative Regulation Of Gene Expression Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process Nuclear Speck Regulation Of Macromolecule Biosynthetic Process U4 SnRNA 3'-end Processing Macromolecule Metabolic Process
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