ULK2 and SYNGAP1

Number of citations of the paper that reports this interaction (PMID 15014045)
48

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		ULK2	SYNGAP1
Gene Name		unc-51 like autophagy activating kinase 2	synaptic Ras GTPase activating protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Membrane Pre-autophagosomal Structure Membrane ATG1/UKL1 Signaling Complex	Cytoplasm Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Dendritic Shaft
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Rab GTPase Activator Activity Ras GTPase Activator Activity SH3 Domain Binding
	Biological Process	Autophagic Vacuole Assembly Signal Transduction Regulation Of Autophagy Response To Starvation Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension	Ras Protein Signal Transduction Pattern Specification Process Visual Learning Dendrite Development Positive Regulation Of Ras GTPase Activity Positive Regulation Of Rab GTPase Activity Receptor Clustering Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Axonogenesis Regulation Of Synapse Structure Or Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: DIXDC1 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 SETDB1 SQSTM1 SYNGAP1 ZNF32	13 interactors: CAMK2A DLG3 DLG4 DLGAP4 GRIN1 GRIN2B GRIN2D KDR MPDZ PDGFRB TRIP6 ULK1 ULK2
Entrez ID		9706	8831
HPRD ID		10556	16018
Ensembl ID		ENSG00000083290	ENSG00000197283
Uniprot IDs		Q8IYT8	Q96PV0
PDB IDs
Enriched GO Terms of Interacting Partners?		Macroautophagy Cellular Response To Starvation Nucleophagy Autophagy Mitochondrion Degradation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Cellular Component Assembly Protein Localization Organelle Disassembly Autophagic Vacuole Assembly Response To Nutrient Levels Blastocyst Development Vacuole Organization Response To Extracellular Stimulus Membrane Fusion Regulation Of Axonogenesis Forebrain Ventricular Zone Progenitor Cell Division Protein Transport Negative Regulation Of Neuron Differentiation Cellular Localization Establishment Of Protein Localization Histone H3-K9 Trimethylation DNA Replication-dependent Nucleosome Assembly Cellular Metabolic Process Cell Proliferation	Protein Autophosphorylation Cell-cell Signaling Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Signaling Startle Response Cell Communication Neuron Projection Morphogenesis Neuromuscular Process Cell Development Cell Morphogenesis Involved In Differentiation Response To External Stimulus Locomotion Regulation Of Synaptic Plasticity Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Signal Transduction Cell Part Morphogenesis Regulation Of Neuronal Synaptic Plasticity Movement Of Cell Or Subcellular Component Glutamate Receptor Signaling Pathway Negative Regulation Of Collateral Sprouting Neuron Development Neuron-neuron Synaptic Transmission Receptor Localization To Synapse Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Anatomical Structure Morphogenesis Cell Morphogenesis Chemotaxis Neuron Differentiation Cell Projection Organization Regulation Of Synaptic Transmission Phosphorylation Membrane Depolarization Cellular Response To Stimulus Protein Localization To Synapse Axon Guidance Learning System Development Regulation Of Signaling Suckling Behavior Nervous System Development Regulation Of Axonogenesis Single-organism Behavior Generation Of Neurons
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a visualized	asah1 atypical broadening canada care4rare causal definitive descriptions encephalopathy epilepsy exome families folr1 forge grin2a kcnq2 nation projects rare recognizable retrospect scn8a segregating seizures suited synj1 translating unrevealing wes
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a visualized	asah1 atypical broadening canada care4rare causal definitive descriptions encephalopathy epilepsy exome families folr1 forge grin2a kcnq2 nation projects rare recognizable retrospect scn8a segregating seizures suited synj1 translating unrevealing wes
Tagcloud (Intersection) ?