ULK2 and EEF1B2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ULK2	EEF1B2
Gene Name		unc-51 like autophagy activating kinase 2	eukaryotic translation elongation factor 1 beta 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Membrane Pre-autophagosomal Structure Membrane ATG1/UKL1 Signaling Complex	Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Translation Elongation Factor Activity Protein Binding
	Biological Process	Autophagic Vacuole Assembly Signal Transduction Regulation Of Autophagy Response To Starvation Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension	Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process
Pathways			Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: DIXDC1 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 SETDB1 SQSTM1 SYNGAP1 ZNF32	10 interactors: AARS APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS TIMP1 ULK2 VHL
Entrez ID		9706	1933
HPRD ID		10556	02804
Ensembl ID		ENSG00000083290	ENSG00000114942
Uniprot IDs		Q8IYT8	P24534
PDB IDs			1B64
Enriched GO Terms of Interacting Partners?		Macroautophagy Cellular Response To Starvation Nucleophagy Autophagy Mitochondrion Degradation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Cellular Component Assembly Protein Localization Organelle Disassembly Autophagic Vacuole Assembly Response To Nutrient Levels Blastocyst Development Vacuole Organization Response To Extracellular Stimulus Membrane Fusion Regulation Of Axonogenesis Forebrain Ventricular Zone Progenitor Cell Division Protein Transport Negative Regulation Of Neuron Differentiation Cellular Localization Establishment Of Protein Localization Histone H3-K9 Trimethylation DNA Replication-dependent Nucleosome Assembly Cellular Metabolic Process Cell Proliferation	Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Neuromuscular Process Response To External Stimulus Regulation Of Cell Cycle Process Cell Morphogenesis Cellular Protein Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Regulation Of Mitotic Cell Cycle Phase Transition Neuron Projection Morphogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Proteolysis Nervous System Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Cell Division Negative Regulation Of Endopeptidase Activity Cell Morphogenesis Involved In Differentiation Negative Regulation Of Peptidase Activity Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Negative Regulation Of Catalytic Activity Regulation Of Mitotic Metaphase/anaphase Transition Generation Of Neurons Developmental Process Negative Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Negative Regulation Of Cell Development Visual Learning Cell Part Morphogenesis Neurogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Visual Behavior Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Apoptotic Process Platelet Degranulation
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a visualized	aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a visualized	aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox
Tagcloud (Intersection) ?