ULK2 and DIXDC1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ULK2	DIXDC1
Gene Name		unc-51 like autophagy activating kinase 2	DIX domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Membrane Pre-autophagosomal Structure Membrane ATG1/UKL1 Signaling Complex	Cytosol Focal Adhesion Neuronal Cell Body Protein Complex Axon Terminus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Actin Binding Protein Binding Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Gamma-tubulin Binding
	Biological Process	Autophagic Vacuole Assembly Signal Transduction Regulation Of Autophagy Response To Starvation Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension	Cell Cycle Wnt Signaling Pathway Cerebellar Cortex Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Neuron Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Axonogenesis Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: DIXDC1 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 SETDB1 SQSTM1 SYNGAP1 ZNF32	8 interactors: APP ATXN1 AXIN1 CDC5L MAP3K4 NDEL1 ULK2 ZDHHC17
Entrez ID		9706	85458
HPRD ID		10556	16804
Ensembl ID		ENSG00000083290	ENSG00000150764
Uniprot IDs		Q8IYT8	E9PRV4 Q155Q3 Q86SR7
PDB IDs			3PZ7
Enriched GO Terms of Interacting Partners?		Macroautophagy Cellular Response To Starvation Nucleophagy Autophagy Mitochondrion Degradation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Cellular Component Assembly Protein Localization Organelle Disassembly Autophagic Vacuole Assembly Response To Nutrient Levels Blastocyst Development Vacuole Organization Response To Extracellular Stimulus Membrane Fusion Regulation Of Axonogenesis Forebrain Ventricular Zone Progenitor Cell Division Protein Transport Negative Regulation Of Neuron Differentiation Cellular Localization Establishment Of Protein Localization Histone H3-K9 Trimethylation DNA Replication-dependent Nucleosome Assembly Cellular Metabolic Process Cell Proliferation	Developmental Cell Growth Developmental Growth Involved In Morphogenesis Cell Growth Regulation Of Signal Transduction Developmental Growth Regulation Of Developmental Growth Regulation Of Signaling Axon Cargo Transport Response To Light Stimulus Neuron Projection Extension Visual Learning Visual Behavior Positive Regulation Of JUN Kinase Activity Signaling Neuron Differentiation Cell Communication Forebrain Development Regulation Of JUN Kinase Activity Associative Learning Wnt-activated Signaling Pathway Involved In Forebrain Neuron Fate Commitment Canonical Wnt Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Response To Radiation Growth Regulation Of Phosphorylation Axonogenesis System Development Regulation Of Neuron Differentiation Adult Locomotory Behavior Synaptic Growth At Neuromuscular Junction Male Germ-line Sex Determination Axon Development RNA Processing Positive Regulation Of JNK Cascade Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Size Microtubule-based Transport Regulation Of Phosphorus Metabolic Process Regulation Of Growth Positive Regulation Of Stress-activated MAPK Cascade Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Learning Intracellular Transport Positive Regulation Of Catalytic Activity Activation Of MAPK Activity Neuron Projection Morphogenesis Collateral Sprouting In Absence Of Injury Primary Sex Determination Axial Mesoderm Formation Generation Of Neurons
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a visualized	angiogenic array catenin gained gsk3beta hey huaier invasiveness ip1 kill knocking lrp6 mobility motility murr ovarian phosphorylations popularity robiniophila rppa s9 scratch skov3 srb trametes untreated viability wnt5a xenografts
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a visualized	angiogenic array catenin gained gsk3beta hey huaier invasiveness ip1 kill knocking lrp6 mobility motility murr ovarian phosphorylations popularity robiniophila rppa s9 scratch skov3 srb trametes untreated viability wnt5a xenografts
Tagcloud (Intersection) ?