IPO13 and NPSR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		IPO13	NPSR1
Description		importin 13	neuropeptide S receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Small GTPase Binding	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs			Halothane
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		20 interacting genes: ALX1 ARX CRX EIF1AX GK HMBOX1 MAGOH NOSIP NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RNF10 RPL5 UBE2I	16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101
Entrez ID		9670	387129
HPRD ID		13742	10547
Ensembl ID		ENSG00000117408	ENSG00000187258
Uniprot IDs		O94829	A0A090N8Z1 Q6W5P4
PDB IDs		2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?		Translation Initiation Factor Activity Chromatin Translational Initiation Exon-exon Junction Subcomplex Mago-y14 Cytosol Sequence-specific Double-stranded DNA Binding Nuclear Export Nuclear Transport Nucleocytoplasmic Transport RNA Transport RNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Neuron Development Translation Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex RNA Export From Nucleus Nuclear Pore Nucleobase-containing Compound Transport Translation Factor Activity, RNA Binding Exon-exon Junction Complex Cell Development Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Nucleoplasm Pronuclear Fusion Regulation Of Macromolecule Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Chromatin Binding Cytoplasm Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Glycerol Kinase Activity Glycerol-3-phosphate Biosynthetic Process MRNA Transport Sequence-specific DNA Binding Forebrain-midbrain Boundary Formation Pituitary Gland Development Pancreatic A Cell Development SUMO Conjugating Enzyme Activity Structural Constituent Of Presynapse Cytoplasmic Translational Initiation	Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity
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