NPSR1 and PGM2L1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		NPSR1	PGM2L1
Description		neuropeptide S receptor 1	phosphoglucomutase 2 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Cytoplasm Cytosol
	Molecular Function	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity	Catalytic Activity Transferase Activity Isomerase Activity Intramolecular Phosphotransferase Activity Metal Ion Binding Glucose-1,6-bisphosphate Synthase Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation	Carbohydrate Metabolic Process Glucose Metabolic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events	Glycolysis
Drugs		Halothane
Diseases
GWAS		Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hippocampal atrophy ( 25625606)
Interacting Genes		16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101	1 interacting genes: NPSR1
Entrez ID		387129	283209
HPRD ID		10547	11427
Ensembl ID		ENSG00000187258	ENSG00000165434
Uniprot IDs		A0A090N8Z1 Q6W5P4	Q6PCE3
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity	Negative Regulation Of Defecation Negative Regulation Of Eating Behavior Righting Reflex Negative Regulation Of Feeding Behavior Regulation Of Eating Behavior Vasopressin Receptor Activity Reflex Neuropeptide Receptor Activity Regulation Of Feeding Behavior Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcium Ion Transmembrane Transport Feeding Behavior Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Behavior Neuropeptide Signaling Pathway Positive Regulation Of Calcium Ion Transport Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Sequestering Of Calcium Ion Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Secretion Positive Regulation Of Monoatomic Ion Transport Regulation Of Calcium Ion Transport Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of ERK1 And ERK2 Cascade Regulation Of Metal Ion Transport G Protein-coupled Receptor Activity Regulation Of Monoatomic Ion Transport Negative Regulation Of Transport
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