NPSR1 and SLC41A3

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		NPSR1	SLC41A3
Description		neuropeptide S receptor 1	solute carrier family 41 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Magnesium:sodium Antiporter Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transmembrane Transport Mitochondrial Magnesium Ion Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs		Halothane
Diseases
GWAS		Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)	Bell's palsy ( 33602968)
Interacting Genes		16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101	17 interacting genes: APP ARLN CCL3L3 CCR2 CREB3 GPR37 IGFBP5 MAPK6 NHERF4 NPSR1 PLP1 REL SMCO4 SMO SUFU TMBIM6 TSPO2
Entrez ID		387129	54946
HPRD ID		10547	11580
Ensembl ID		ENSG00000187258	ENSG00000114544
Uniprot IDs		A0A090N8Z1 Q6W5P4	Q96GZ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity	Positive Regulation Of Monocyte Chemotaxis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Signal Transduction Positive Regulation Of Locomotion Locomotion Regulation Of Signal Transduction Spinal Cord Dorsal/ventral Patterning Regulation Of Calcium Ion Transport G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Astrocyte Activation Neuropeptide Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Migration Chemotaxis Regulation Of Metal Ion Transport Regulation Of Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Locomotion Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Endoplasmic Reticulum Positive Regulation Of Leukocyte Migration G Protein-coupled Receptor Activity Hair Follicle Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Transport Amyloid-beta Complex Growth Cone Lamellipodium Intracellular Signal Transduction Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Positive Regulation Of Cell Communication Dendrite Amylin Binding Positive Regulation Of Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of T Cell Migration Positive Regulation Of Signal Transduction Dendrite Development
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