NPSR1 and PRR36

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		NPSR1	PRR36
Description		neuropeptide S receptor 1	proline rich 36
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs		Halothane
Diseases
GWAS		Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)	Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101	2 interacting genes: NPSR1 PELI2
Entrez ID		387129	80164
HPRD ID		10547	18916
Ensembl ID		ENSG00000187258	ENSG00000183248
Uniprot IDs		A0A090N8Z1 Q6W5P4	Q9H6K5
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity	Negative Regulation Of Defecation Regulation Of Toll Signaling Pathway Positive Regulation Of MAPK Cascade Righting Reflex Negative Regulation Of Feeding Behavior Regulation Of Eating Behavior Negative Regulation Of Eating Behavior Vasopressin Receptor Activity Regulation Of MAPK Cascade Ubiquitin-ubiquitin Ligase Activity Reflex Neuropeptide Receptor Activity Regulation Of Feeding Behavior Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Signal Transduction Regulation Of Behavior Feeding Behavior Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication Positive Regulation Of Signaling Neuropeptide Signaling Pathway Positive Regulation Of Calcium Ion Transport Regulation Of Intracellular Signal Transduction Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport
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