NPSR1 and TMEM101

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		NPSR1	TMEM101
Description		neuropeptide S receptor 1	transmembrane protein 101
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Membrane
	Molecular Function	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation	Positive Regulation Of Canonical NF-kappaB Signal Transduction
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs		Halothane
Diseases
GWAS		Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101	21 interacting genes: ACKR5 ARLN BNIP3 CCR4 DRD2 GIMAP1 MAP4K1 NDUFA3 NINJ2 NPSR1 PDZK1IP1 PKMYT1 STRIT1 STX10 SYNJ2BP TMEM243 TMEM65 TMIE VAMP1 VAMP2 VAPB
Entrez ID		387129	84336
HPRD ID		10547	14623
Ensembl ID		ENSG00000187258	ENSG00000091947
Uniprot IDs		A0A090N8Z1 Q6W5P4	B4DFS4 Q96IK0
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity	Membrane Synaptic Vesicle Membrane SNARE Complex SNAP Receptor Activity Syntaxin Binding Mitochondrial Outer Membrane SNARE Complex Assembly Interneuron Migration Vesicle Fusion Organelle Membrane Fusion Vesicle Organization Organelle Fusion
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