ZNF592 and GRIK1

  • Number of citations: 83 (PubMedID 35914814)
  • Data Source: BioGRID (two hybrid)

ZNF592

GRIK1

Name zinc finger protein 592 glutamate ionotropic receptor kainate type subunit 1
Structure No pdb structure PDB 2ZNS
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways None
Drugs None
Diseases None
GWAS
  • Alzheimer's disease (age of onset) ( 22005931 )
  • Autism spectrum disorder or schizophrenia ( 28540026 )
  • Bipolar disorder ( 31043756 33263727 34002096 )
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 )
  • Electrocardiographic traits (multivariate) ( 32602732 )
  • Hypertrophic cardiomyopathy ( 33495596 )
  • Hypertrophic cardiomyopathy (MTAG) ( 33495596 )
  • Schizophrenia ( 29483656 )
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885 )
  • Body mass index ( 22446040 )
  • Breast cancer ( 17903305 )
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444 )
  • Forehead morphology ( 29921221 )
  • Generalized epilepsy ( 30531953 )
  • Glucocorticoid-induced osteonecrosis ( 26265699 )
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883 )
  • Hepatocellular carcinoma ( 22807686 )
  • Hyperactive-impulsive symptoms ( 18821565 )
  • Lung cancer ( 34062886 )
  • Periodontitis (DPAL) ( 24024966 )
  • Plasma parathyroid hormone levels ( 30134803 )
  • Refractive error ( 32231278 )
  • Response to statin therapy ( 20339536 )
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027 )
Novel Interactors 2 novel interactors: AGBL1 LINC00052 1 novel interactors: IFNGR2
Interacting Genes 6 interacting genes: BTG3 GRIK1 LAMTOR5 SMAD9 SRPK2 TCAF1 31 interacting genes: COPS5 CYSLTR2 DLG4 DLST DNAJB9 FLNA GORASP2 GRIK2 GRIK3 GRIK4 GRIK5 GRIP1 HOMER1 HSP90B1 KALRN KCNQ2 LDB2 PICK1 PTPRD RANBP9 RNF123 SDCBP SEPTIN7 SIPA1L3 SNAPIN SRI ST13 TAAR1 UBE2O ZFC3H1 ZNF592
Entrez ID 9640 2897
HPRD ID 10339 00693
Ensembl ID ENSG00000166716 ENSG00000171189
Uniprot IDs Q92610 B7Z256 B7Z3V7 E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086
PDB IDs Not available 2ZNS 2ZNT 2ZNU 3FUZ 3FV1 3FV2 3FVG 3FVK 3FVN 3FVO 4MF3
GO Terms Enriched among Interactors None