ZNF592 and TCAF1

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		ZNF592	TCAF1
Name		zinc finger protein 592	TRPM8 channel associated factor 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding PH Domain Binding Insulin Receptor Substrate Binding Metal Ion Binding	Protein Binding Transmembrane Transporter Binding
	Biological Process	Regulation Of DNA-templated Transcription Negative Regulation Of Insulin Receptor Signaling Pathway	Negative Regulation Of Cell Migration Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Anion Channel Activity
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)	None
GWAS		Alzheimer's disease (age of onset) ( 22005931 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Bipolar disorder ( 31043756 33263727 34002096 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Electrocardiographic traits (multivariate) ( 32602732 ) Hypertrophic cardiomyopathy ( 33495596 ) Hypertrophic cardiomyopathy (MTAG) ( 33495596 ) Schizophrenia ( 29483656 )	No GWAS studies recorded
Novel Interactors		2 novel interactors: AGBL1 LINC00052	None recorded
Interacting Genes		6 interacting genes: BTG3 GRIK1 LAMTOR5 SMAD9 SRPK2 TCAF1	36 interacting genes: BIRC2 CAMK2A CEP70 CNKSR1 COIL CYSRT1 DISC1 EFEMP2 IKZF3 IKZF4 KRTAP1-3 KRTAP10-8 KRTAP13-2 KRTAP6-3 MAD1L1 MID2 NBPF19 NFYA PRDM14 PRDM6 RBAK SCYL3 SF3B4 SPRY2 TAX1BP1 TCF3 TFIP11 TRAF2 TRIM42 TRIM54 TRIP6 UBC ZNF143 ZNF24 ZNF263 ZNF592
Entrez ID		9640	9747
HPRD ID		10339	13813
Ensembl ID		ENSG00000166716	ENSG00000198420
Uniprot IDs		Q92610	B4DST7 Q9Y4C2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Zinc Ion Binding Identical Protein Binding