NUP155 and ZFYVE9

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
HPRD (two hybrid)

		NUP155	ZFYVE9
Description		nucleoporin 155	zinc finger FYVE-type containing 9
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Membrane Nuclear Pore Inner Ring	Cytoplasm Endosome Early Endosome Cytosol Membrane Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	Protein Binding 1-phosphatidylinositol Binding Zinc Ion Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery RNA Export From Nucleus MRNA Export From Nucleus Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Envelope Organization Protein Transport Protein Localization To Nucleus MiRNA Processing Protein Localization To Nuclear Inner Membrane MRNA Transport Atrial Cardiac Muscle Cell Action Potential	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Malaria ( 31844061) Meat-related diet ( 32066663)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: CDC42 EFS GLE1 NUP35 PDCD6IP UBC ZFYVE9	38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		9631	9372
HPRD ID		05984	04782
Ensembl ID		ENSG00000113569	ENSG00000157077
Uniprot IDs		B4DLT2 E9PF10 O75694	O95405
PDB IDs		5A9Q 5IJN 5IJO 7EYE 7EYF 7EYQ 7PER 7R1Y 7R5J 7R5K	1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?		Apolipoprotein A-I Receptor Binding Cellular Localization Endothelin Receptor Signaling Pathway Involved In Heart Process Focal Adhesion Establishment Or Maintenance Of Apical/basal Cell Polarity Centrosome Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Establishment Of Localization In Cell Intracellular Transport Establishment Or Maintenance Of Cell Polarity RNA Transport Inositol Hexakisphosphate Binding Nuclear Pore Cytoplasmic Filaments Phospholipid Binding MRNA Transport Nuclear Pore Extracellular Vesicle Biogenesis Extracellular Exosome Biogenesis Nucleus Organization Positive Regulation Of Extracellular Exosome Assembly Proteinase Activated Receptor Binding Actomyosin Contractile Ring Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell-cell Junction Organization Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Extracellular Exosome Assembly Nuclear Pore Central Transport Channel Intracellular Protein Localization Nucleobase-containing Compound Transport Nuclear Envelope Establishment Of Golgi Localization Protein Domain Specific Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Leading Edge Membrane Thioesterase Binding Neuron Fate Determination Golgi Transport Complex Actomyosin Nuclear Transport Nucleocytoplasmic Transport Endothelin Receptor Signaling Pathway Cell Junction Assembly Cytosol	Embryonic Cranial Skeleton Morphogenesis Positive Regulation Of Epithelial To Mesenchymal Transition Ubiquitin Protein Ligase Binding Embryonic Skeletal System Morphogenesis I-SMAD Binding SMAD Binding Lung Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Skeletal System Morphogenesis Entrainment Of Circadian Clock By Photoperiod Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Signal Transduction Trachea Formation Trophoblast Cell Migration PTW/PP1 Phosphatase Complex Embryonic Organ Morphogenesis Photoperiodism Entrainment Of Circadian Clock Activin Receptor Signaling Pathway Embryonic Foregut Morphogenesis Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Cell Fate Commitment Tissue Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Tissue Development Gastrulation Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Branching Involved In Lung Morphogenesis Tube Morphogenesis Positive Regulation Of Developmental Process Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription Elongation By RNA Polymerase II Mesenchyme Development Regulation Of Developmental Process Formation Of Primary Germ Layer Branching Morphogenesis Of An Epithelial Tube Osteoblast Differentiation Bronchus Development Animal Organ Formation Positive Regulation Of DNA-templated Transcription, Elongation Catenin-TCF7L2 Complex Paraxial Mesoderm Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Regulation Of Translation In Response To Stress Circadian Regulation Of Gene Expression In Utero Embryonic Development Regulation Of SMAD Protein Signal Transduction Developmental Growth
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