RNF7 and UBE2F

Number of citations of the paper that reports this interaction (PubMedID 36253371)
50

Data Source:
BioGRID (pull down)

		RNF7	UBE2F
Description		ring finger protein 7	ubiquitin conjugating enzyme E2 F (putative)
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cul5-RING Ubiquitin Ligase Complex	Nucleus Cytosol
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding Transferase Activity NEDD8 Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	Nucleotide Binding Protein Binding ATP Binding Transferase Activity NEDD8 Transferase Activity NEDD8 Conjugating Enzyme Activity NEDD8 Ligase Activity
	Biological Process	Epithelial To Mesenchymal Transition Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Ubiquitination Layer Formation In Cerebral Cortex Positive Regulation Of Cell Migration Endoplasmic Reticulum Unfolded Protein Response SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Reelin-mediated Signaling Pathway Erythropoietin-mediated Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Innate Immune Response Protein Neddylation Phosphocreatine Biosynthetic Process Defense Response To Virus Response To Redox State Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Growth Hormone Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Growth Hormone Receptor Signaling Pathway Protein K11-linked Ubiquitination Negative Regulation Of Focal Adhesion Disassembly CGAS/STING Signaling Pathway Regulation Of Neuron Migration	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Innate Immune Response Protein Neddylation Defense Response To Virus
Pathways		Neddylation Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)	Lean body mass ( 28552196)
Interacting Genes		43 interacting genes: APOBEC3F APOBEC3G ARIH2 ASB11 BTRC CASP7 CBFB CDC34 CHFR CREBBP CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL5 CYCS ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBA3 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 USP40	13 interacting genes: CUL1 DCUN1D1 DCUN1D2 DCUN1D5 LCN2 NAE1 PAX6 RBX1 RC3H1 RNF34 RNF7 TRIM2 UBA3
Entrez ID		9616	140739
HPRD ID		04840	14812
Ensembl ID		ENSG00000114125	ENSG00000184182
Uniprot IDs		Q9UBF6	Q969M7
PDB IDs		2ECL 7ONI	2EDI 3FN1 4GBA
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Ubiquitination Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Proteolysis Involved In Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Metabolic Process Macromolecule Catabolic Process Proteolysis Protein K48-linked Ubiquitination Macromolecule Metabolic Process Protein Catabolic Process Ubiquitin Conjugating Enzyme Activity Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cullin-RING Ubiquitin Ligase Complex Ubiquitin Protein Ligase Activity Ubiquitin Ligase Complex Scaffold Activity Nucleus Cell Cycle Phase Transition Cul5-RING Ubiquitin Ligase Complex Protein K11-linked Ubiquitination Transferase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Mitotic Cell Cycle Phase Transition NEDD8 Transferase Activity Cytosol Ubiquitin Ligase Complex SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Virus Defense Response To Virus Intracellular Signal Transduction Protein K63-linked Ubiquitination Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway NEDD8 Conjugating Enzyme Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Catabolic Process Ubiquitin Protein Ligase Binding Protein Monoubiquitination Regulation Of Protein Metabolic Process Cul2-RING Ubiquitin Ligase Complex Ubiquitin-like Protein Transferase Activity Protein Destabilization	Protein Neddylation Protein Modification By Small Protein Conjugation Post-translational Protein Modification Cullin Family Protein Binding Protein Modification Process NEDD8 Transferase Activity Ubiquitin-like Protein Binding Positive Regulation Of Protein Neddylation Protein Polyubiquitination Protein Metabolic Process Regulation Of Protein Neddylation NEDD8 Activating Enzyme Activity Ubiquitin Protein Ligase Binding Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Ubiquitin Conjugating Enzyme Binding Positive Regulation Of Post-translational Protein Modification Macromolecule Metabolic Process Protein Ubiquitination NEDD8 Ligase Activity Ubiquitin Protein Ligase Activity Proteolysis Involved In Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-like Modifier Activating Enzyme Activity Regulation Of Post-translational Protein Modification Cullin-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Macromolecule Catabolic Process Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin Ligase Complex Positive Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Protein Modification Process Cytoplasm Cellular Response To Cytokine Stimulus Regulation Of Apoptotic Process Apoptotic Process Regulation Of Programmed Cell Death Programmed Cell Death Cell Death Cellular Response To Oxidative Stress Negative Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Stress Response To Cytokine Response To Peptide Cellular Response To Interleukin-1 Positive Regulation Of Hippocampal Neuron Apoptotic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?