RNF7 and PLA2G15

Number of citations of the paper that reports this interaction (PMID 10230407)
134

Data Source:
HPRD (two hybrid, in vivo)

		RNF7	PLA2G15
Gene Name		ring finger protein 7	phospholipase A2, group XV
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cul5-RING Ubiquitin Ligase Complex	Mitochondrion Lysosome Extracellular Vesicular Exosome
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Cullin Family Protein Binding	Lysophospholipase Activity Phospholipid Binding O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity
	Biological Process	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Protein Ubiquitination Negative Regulation Of Apoptotic Process Protein Neddylation Response To Redox State	Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Metabolic Process
Pathways
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784)
Protein-Protein Interactions		34 interactors: ASB2 CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS GEM GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L NFKBIA PLA2G15 TCEB1 TCEB2 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2M UBE2Q1	2 interactors: IMMT RNF7
Entrez ID		9616	23659
HPRD ID		04840	07128
Ensembl ID			ENSG00000103066
Uniprot IDs		Q9UBF6	B4DJW4 B4DUD1 Q8NCC3
PDB IDs		2ECL
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Metabolic Process Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Viral Process Regulation Of DNA-templated Transcription In Response To Stress Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Proteolysis Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Protein K48-linked Ubiquitination Protein Monoubiquitination Positive Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Cell Cycle Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Apoptotic Signaling Pathway Apoptotic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Cellular Response To Stimulus Programmed Cell Death Cellular Metabolic Process Cell Death Death Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Abiotic Stimulus Proteasomal Protein Catabolic Process Cell Cycle Arrest TRIF-dependent Toll-like Receptor Signaling Pathway	Protein Neddylation Response To Redox State Mitochondrial Calcium Ion Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Cold
Tagcloud ?		biologically bridges consistently cul degraded e3 etoposide hect ligase ligases list nedd4 proteasome rbx2 redox ring roc2 sag scf sensitizes shortened substrates terminus transcriptionally tri ubiquitin ubiquitylated ubiquitylates ubiquitylation
Tagcloud (Difference) ?		biologically bridges consistently cul degraded e3 etoposide hect ligase ligases list nedd4 proteasome rbx2 redox ring roc2 sag scf sensitizes shortened substrates terminus transcriptionally tri ubiquitin ubiquitylated ubiquitylates ubiquitylation
Tagcloud (Intersection) ?