RNF7 and ASB11

Number of citations of the paper that reports this interaction (PubMedID 31387940)
57

Data Source:
BioGRID (pull down)

		RNF7	ASB11
Description		ring finger protein 7	ankyrin repeat and SOCS box containing 11
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cul5-RING Ubiquitin Ligase Complex	Endoplasmic Reticulum Cytosol Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding Transferase Activity NEDD8 Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Epithelial To Mesenchymal Transition Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Ubiquitination Layer Formation In Cerebral Cortex Positive Regulation Of Cell Migration Endoplasmic Reticulum Unfolded Protein Response SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Reelin-mediated Signaling Pathway Erythropoietin-mediated Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Innate Immune Response Protein Neddylation Phosphocreatine Biosynthetic Process Defense Response To Virus Response To Redox State Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Growth Hormone Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Growth Hormone Receptor Signaling Pathway Protein K11-linked Ubiquitination Negative Regulation Of Focal Adhesion Disassembly CGAS/STING Signaling Pathway Regulation Of Neuron Migration	Protein Ubiquitination Endoplasmic Reticulum Unfolded Protein Response Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Protein K11-linked Ubiquitination
Pathways		Neddylation Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)	vascular endothelial growth factor D levels ( 25147954)
Interacting Genes		43 interacting genes: APOBEC3F APOBEC3G ARIH2 ASB11 BTRC CASP7 CBFB CDC34 CHFR CREBBP CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL5 CYCS ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBA3 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 USP40	7 interacting genes: BIK CUL5 ELOB ELOC PAICS RNF7 UBC
Entrez ID		9616	140456
HPRD ID		04840	06450
Ensembl ID		ENSG00000114125	ENSG00000165192
Uniprot IDs		Q9UBF6	Q8WXH4
PDB IDs		2ECL 7ONI	4UUC
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Ubiquitination Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Proteolysis Involved In Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Metabolic Process Macromolecule Catabolic Process Proteolysis Protein K48-linked Ubiquitination Macromolecule Metabolic Process Protein Catabolic Process Ubiquitin Conjugating Enzyme Activity Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cullin-RING Ubiquitin Ligase Complex Ubiquitin Protein Ligase Activity Ubiquitin Ligase Complex Scaffold Activity Nucleus Cell Cycle Phase Transition Cul5-RING Ubiquitin Ligase Complex Protein K11-linked Ubiquitination Transferase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Mitotic Cell Cycle Phase Transition NEDD8 Transferase Activity Cytosol Ubiquitin Ligase Complex SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Virus Defense Response To Virus Intracellular Signal Transduction Protein K63-linked Ubiquitination Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway NEDD8 Conjugating Enzyme Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Catabolic Process Ubiquitin Protein Ligase Binding Protein Monoubiquitination Regulation Of Protein Metabolic Process Cul2-RING Ubiquitin Ligase Complex Ubiquitin-like Protein Transferase Activity Protein Destabilization	Cul5-RING Ubiquitin Ligase Complex Target-directed MiRNA Degradation Elongin Complex Negative Regulation Of Focal Adhesion Disassembly Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Erythropoietin-mediated Signaling Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway MiRNA Catabolic Process Regulation Of Growth Hormone Receptor Signaling Pathway Reelin-mediated Signaling Pathway Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Macromolecule Catabolic Process Negative Regulation Of MiRNA-mediated Gene Silencing Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cul2-RING Ubiquitin Ligase Complex Layer Formation In Cerebral Cortex Negative Regulation Of Focal Adhesion Assembly Modification-dependent Protein Catabolic Process MiRNA Metabolic Process Growth Hormone Receptor Signaling Pathway Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing CGAS/STING Signaling Pathway Positive Regulation Of Focal Adhesion Assembly Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Cell-matrix Adhesion Protein K11-linked Ubiquitination Protein Modification Process Transcription Initiation At RNA Polymerase II Promoter Regulation Of Neuron Migration Transcription Corepressor Binding Ubiquitin Protein Ligase Binding SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell-substrate Adhesion Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Regulation Of Focal Adhesion Assembly DNA-templated Transcription Initiation Regulation Of Cell-substrate Junction Organization Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Phosphoribosylaminoimidazole Carboxylase Activity Epithelial To Mesenchymal Transition Proteolysis Mesenchymal Cell Differentiation Cytoplasmic Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Cell Junction Assembly Symbiont-mediated Suppression Of Host Innate Immune Response
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