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NR1D1 and INPP1
Number of citations of the paper that reports this interaction (PMID
24722188
)
1
Data Source:
BioGRID
(two hybrid)
NR1D1
INPP1
Gene Name
nuclear receptor subfamily 1, group D, member 1
inositol polyphosphate-1-phosphatase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Dendrite
Dendritic Spine
Cytosol
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Transcription Corepressor Binding
Steroid Hormone Receptor Activity
Transcription Corepressor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Heme Binding
Transcription Regulatory Region DNA Binding
Inositol-1,4-bisphosphate 1-phosphatase Activity
Metal Ion Binding
Inositol-1,3,4-trisphosphate 1-phosphatase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Glycogen Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Circadian Rhythm
Gene Expression
Proteasomal Protein Catabolic Process
Negative Regulation Of Receptor Biosynthetic Process
Regulation Of Lipid Metabolic Process
Cell Differentiation
Intracellular Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Circadian Rhythm
Steroid Hormone Mediated Signaling Pathway
Response To Leptin
Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Circadian Temperature Homeostasis
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of Type B Pancreatic Cell Proliferation
Positive Regulation Of Bile Acid Biosynthetic Process
Cellular Response To Lipopolysaccharide
Regulation Of Cholesterol Homeostasis
Positive Regulation Of Cholesterol Homeostasis
Phosphate-containing Compound Metabolic Process
Signal Transduction
Dephosphorylation
Inositol Phosphate Metabolic Process
Small Molecule Metabolic Process
Phosphatidylinositol Phosphorylation
Pathways
PPARA activates gene expression
Organelle biogenesis and maintenance
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Nuclear Receptor transcription pathway
REV-ERBA represses gene expression
RORA activates circadian gene expression
Mitochondrial biogenesis
Generic Transcription Pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Transcriptional activation of mitochondrial biogenesis
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Synthesis of IP2, IP, and Ins in the cytosol
Inositol phosphate metabolism
Drugs
Diseases
GWAS
White blood cell count (
21738480
)
Protein-Protein Interactions
7 interactors:
APP
C1D
INPP1
NCOR1
NCOR2
NR1D2
NR2E3
11 interactors:
BRCA1
C9orf16
DYNLL1
LDOC1
LIG1
MEOX2
NDC80
NECAB2
NR1D1
SYCE3
USHBP1
Entrez ID
9572
3628
HPRD ID
03873
00923
Ensembl ID
ENSG00000126368
ENSG00000151689
Uniprot IDs
F1D8S3
P20393
P49441
Q6IBG4
PDB IDs
1A6Y
1EF6
1GA5
1HLZ
3N00
Enriched GO Terms of Interacting Partners
?
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Notch Signaling Pathway
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Intracellular Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Chemical Homeostasis
Transcription From RNA Polymerase II Promoter
Gene Expression
Rhythmic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Forebrain Development
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Lipid Metabolic Process
Response To Steroid Hormone
Regulation Of RNA Metabolic Process
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Homeostatic Process
Regulation Of Multicellular Organism Growth
Steroid Hormone Mediated Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Lipid Homeostasis
Cellular Nitrogen Compound Metabolic Process
Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Growth At Neuromuscular Junction
Signal Transduction
Hormone-mediated Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Rhodopsin Gene Expression
CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation
Nitrogen Compound Metabolic Process
Signaling
Brain Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Cell Cycle Process
Cell Cycle
Chromosome Segregation
DNA Recombination
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Bile Acid Biosynthetic Process
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Cell Division
Circadian Temperature Homeostasis
Positive Regulation Of Histone H3-K9 Acetylation
Regulation Of Type B Pancreatic Cell Proliferation
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Lipid Biosynthetic Process
Double-strand Break Repair
Otolith Morphogenesis
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Cellular Response To Indole-3-methanol
Negative Regulation Of Centriole Replication
Negative Regulation Of Receptor Biosynthetic Process
Lagging Strand Elongation
Somite Specification
Intrinsic Apoptotic Signaling Pathway
Mitotic Cell Cycle
Microtubule-based Process
Nucleobase-containing Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Otolith Development
Dosage Compensation By Inactivation Of X Chromosome
Protein K6-linked Ubiquitination
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter
DNA Ligation Involved In DNA Repair
Regulation Of Histone H3-K9 Acetylation
Organelle Organization
Cellular Nitrogen Compound Metabolic Process
Attachment Of Spindle Microtubules To Kinetochore
DNA Replication
Regulation Of Centriole Replication
Positive Regulation Of Histone H3-K4 Methylation
DNA Ligation
Regulation Of Histone H4 Acetylation
Negative Regulation Of Fatty Acid Biosynthetic Process
Tagcloud
?
arntl2
atlantic
clock
clocks
cry1b
cry2
cry3
cryptochrome
gadus
kaput
mbnl1
minded
morhua
muscleblind
myf5
npas1
npas2
nr1d2a
ontogenesis
oscillators
per2a
per2b
rhythmicity
rora
synteny
teleosts
tetrapods
timeless
translocator
Tagcloud (Difference)
?
arntl2
atlantic
clock
clocks
cry1b
cry2
cry3
cryptochrome
gadus
kaput
mbnl1
minded
morhua
muscleblind
myf5
npas1
npas2
nr1d2a
ontogenesis
oscillators
per2a
per2b
rhythmicity
rora
synteny
teleosts
tetrapods
timeless
translocator
Tagcloud (Intersection)
?