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NR1D1
Gene Name
nuclear receptor subfamily 1, group D, member 1
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Dendrite
Dendritic Spine
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Transcription Corepressor Binding
Steroid Hormone Receptor Activity
Transcription Corepressor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Heme Binding
Transcription Regulatory Region DNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Glycogen Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Circadian Rhythm
Gene Expression
Proteasomal Protein Catabolic Process
Negative Regulation Of Receptor Biosynthetic Process
Regulation Of Lipid Metabolic Process
Cell Differentiation
Intracellular Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Circadian Rhythm
Steroid Hormone Mediated Signaling Pathway
Response To Leptin
Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Circadian Temperature Homeostasis
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of Type B Pancreatic Cell Proliferation
Positive Regulation Of Bile Acid Biosynthetic Process
Cellular Response To Lipopolysaccharide
Regulation Of Cholesterol Homeostasis
Positive Regulation Of Cholesterol Homeostasis
Pathways
PPARA activates gene expression
Organelle biogenesis and maintenance
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Nuclear Receptor transcription pathway
REV-ERBA represses gene expression
RORA activates circadian gene expression
Mitochondrial biogenesis
Generic Transcription Pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Transcriptional activation of mitochondrial biogenesis
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
White blood cell count (
21738480
)
Protein-protein Interactions
7 interactors:
APP
C1D
INPP1
NCOR1
NCOR2
NR1D2
NR2E3
Entrez ID
9572
HPRD ID
03873
Ensembl ID
ENSG00000126368
Uniprot IDs
F1D8S3
P20393
PDB IDs
1A6Y
1EF6
1GA5
1HLZ
3N00
Enriched GO Terms of Interacting Partners
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Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Notch Signaling Pathway
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Intracellular Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Chemical Homeostasis
Transcription From RNA Polymerase II Promoter
Gene Expression
Rhythmic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Forebrain Development
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Lipid Metabolic Process
Response To Steroid Hormone
Regulation Of RNA Metabolic Process
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Homeostatic Process
Regulation Of Multicellular Organism Growth
Steroid Hormone Mediated Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Lipid Homeostasis
Cellular Nitrogen Compound Metabolic Process
Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Growth At Neuromuscular Junction
Signal Transduction
Hormone-mediated Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Rhodopsin Gene Expression
CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation
Nitrogen Compound Metabolic Process
Signaling
Brain Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Tagcloud
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arntl2
atlantic
clock
clocks
cry1b
cry2
cry3
cryptochrome
gadus
kaput
mbnl1
minded
morhua
muscleblind
myf5
npas1
npas2
nr1d2a
ontogenesis
oscillators
per2a
per2b
rhythmicity
rora
synteny
teleosts
tetrapods
timeless
translocator