ATP5MF and HAP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5MF	HAP1
Description		ATP synthase membrane subunit f	huntingtin associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Nuclear Membrane Proton-transporting ATP Synthase Complex	Nucleus Nucleolus Cytoplasm Mitochondrion Lysosome Endosome Early Endosome Autophagosome Endoplasmic Reticulum Centrosome Centriole Cytosol Cytoskeleton Synaptic Vesicle Actin Cytoskeleton Inclusion Body Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Projection Neuron Projection Dendritic Spine Synapse Presynapse Axon Cytoplasm
	Molecular Function	Proton-transporting ATP Synthase Activity, Rotational Mechanism	Signaling Receptor Binding Protein Binding Myosin Binding Transmembrane Transporter Binding Brain-derived Neurotrophic Factor Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Protein Targeting Exocytosis Autophagy Chemical Synaptic Transmission Brain Development Anterograde Axonal Transport Retrograde Axonal Transport Intracellular Protein Localization Protein Transport Regulation Of Exocytosis Cerebellum Development Hypothalamus Cell Differentiation Neurogenesis Cell Projection Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Neurotrophin Production Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle Transport Along Microtubule Neurotrophin TRK Receptor Signaling Pathway Mitochondrion Distribution Positive Regulation Of Neurogenesis Negative Regulation Of Amyloid-beta Formation Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Non-motile Cilium Assembly
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS			Developmental language disorder (syntactic complexity) ( 27016271) Esophageal cancer (squamous cell) ( 22960999)
Interacting Genes		15 interacting genes: ARL8B CAPNS1 CCDC137 CDC42 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 NECTIN2 PRPF4 RPLP1 TIAM1 ZFPL1	93 interacting genes: AEN ANTKMT APLP1 ATP5MF BARD1 BRD7 C1orf216 C7orf25 C8orf33 CATSPERT CBX8 CCDC13 CDC73 CDK18 CDK5RAP2 CFAP263 COL9A2 CRIP1 DCTN1 DDX49 DEFB1 EIF3E FAM50B FEZ1 GABARAPL2 GADD45G GIT1 GPRASP2 HDAC4 HGS HMOX2 HOXB5 HSPA1A HSPA4 HTT IMMT ING5 KAT5 KAT7 KATNBL1 KBTBD7 KPNA2 LRIF1 LUC7L2 MPP3 MRPS9 MSGN1 NAP1L5 NDUFB9 NEUROD1 NIPSNAP3A NOD2 NOP53 PABPC4 PCM1 PDCD7 PFDN1 PKN1 PPID PPOX PPP1R18 PRPF31 PSMD11 RER1 RHPN1 RIF1 RPS10 RPS25 SCNM1 SNAPIN SRSF4 STX5 TAF1D TBP TIMM17A TNNT1 TNNT3 TOMM20 TSPYL1 UTP3 VIM ZFP1 ZMAT2 ZNF124 ZNF20 ZNF24 ZNF33B ZNF490 ZNF572 ZNF575 ZNF648 ZNF691 ZNF835
Entrez ID		9551	9001
HPRD ID		16520	02972
Ensembl ID		ENSG00000241468	ENSG00000173805
Uniprot IDs		P56134	P54257
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Organelle Localization Wnt Signaling Pathway, Planar Cell Polarity Pathway Cell-cell Junction Focal Adhesion Establishment Of Organelle Localization Microtubule-based Transport Transport Along Microtubule GBD Domain Binding Storage Vacuole Positive Regulation Of Cell Projection Organization Non-canonical Wnt Signaling Pathway Spindle Midzone Cytoskeleton-dependent Intracellular Transport G Protein Activity Cellular Response To CAMP Phosphoric Ester Hydrolase Activity Cellular Response To Raffinose Fructose 1,6-bisphosphate 1-phosphatase Activity Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Cell-cell Contact Zone Coreceptor-mediated Virion Attachment To Host Cell Cellular Anatomical Entity Morphogenesis Susceptibility To T Cell Mediated Cytotoxicity Sperm Mitochondrion Organization Mitochondrion Localization Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Neurotrophin Production Axon Cytoplasm Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Axonal Transport Anterograde Axonal Transport Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Antigen Processing And Presentation Following Phagocytosis Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Viral Exocytosis Regulation Of Plasma Membrane Bounded Cell Projection Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Organelle Transport Along Microtubule Regulation Of Cell Projection Organization Cellular Hypotonic Salinity Response Fusion Of Virus Membrane With Host Plasma Membrane Susceptibility To Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity	Nucleus Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Establishment Of Mitotic Spindle Localization Establishment Of Mitotic Spindle Orientation Mitotic Spindle Pole DNA Replication-dependent Chromatin Disassembly Establishment Of Spindle Orientation Regulation Of Microtubule Nucleation Chromatin Organization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Binding Regulation Of Metabolic Process Establishment Of Spindle Localization Positive Regulation Of Aggrephagy Protein Import Into Mitochondrial Matrix RNA Polymerase Transcription Factor SL1 Complex Histone Acetyltransferase Complex Spindle Localization Regulation Of Microtubule Polymerization Regulation Of Macromolecule Metabolic Process Establishment Of Organelle Localization Centriolar Satellite Male Pronucleus Troponin Complex Protein Acetylation Histone H4K16 Acetyltransferase Activity Gamma-tubulin Binding
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