ATP5MF and NECTIN2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5MF	NECTIN2
Description		ATP synthase membrane subunit f	nectin cell adhesion molecule 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Nuclear Membrane Proton-transporting ATP Synthase Complex	Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Cell Surface Membrane Apical Junction Complex Cell-cell Contact Zone Extracellular Exosome
	Molecular Function	Proton-transporting ATP Synthase Activity, Rotational Mechanism	Virus Receptor Activity Protein Binding Coreceptor Activity Identical Protein Binding Protein Homodimerization Activity Receptor Ligand Activity Cell Adhesion Molecule Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Acrosome Assembly Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immunoglobulin Mediated Immune Response Cytoskeleton Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Spermatid Development Spermatid Nucleus Differentiation Fertilization Fusion Of Virus Membrane With Host Plasma Membrane Sperm Mitochondrion Organization Cellular Anatomical Entity Morphogenesis Positive Regulation Of Mast Cell Activation Natural Killer Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Adhesion Of Symbiont To Host Cilium Organization Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Viral Entry Into Host Cell Symbiont Entry Into Host Cell Coreceptor-mediated Virion Attachment To Host Cell Positive Regulation Of T Cell Receptor Signaling Pathway Establishment Of Localization In Cell Establishment Of Mitochondrion Localization Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS			Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 30498476) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Urate levels ( 31578528)
Interacting Genes		15 interacting genes: ARL8B CAPNS1 CCDC137 CDC42 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 NECTIN2 PRPF4 RPLP1 TIAM1 ZFPL1	38 interacting genes: AFDN ATP5MF CD226 CYSRT1 DUS2 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP5-9 LCE1C LCE1E LCE1F LCE2B LCE2C LCE5A LYRM4 MAPK6 MDFI MEOX2 NBPF19 NECTIN3 NECTIN4 NOTCH2NLA NR4A3 P4HB PICK1 RGS20 SIAH1 TCF4 TGM1 TIGIT USP53
Entrez ID		9551	5819
HPRD ID		16520	02879
Ensembl ID		ENSG00000241468	ENSG00000130202
Uniprot IDs		P56134	Q92692
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3	3R0N 4DFH 4DFI 4HZA 5V52 8X6B
Enriched GO Terms of Interacting Partners?		Organelle Localization Wnt Signaling Pathway, Planar Cell Polarity Pathway Cell-cell Junction Focal Adhesion Establishment Of Organelle Localization Microtubule-based Transport Transport Along Microtubule GBD Domain Binding Storage Vacuole Positive Regulation Of Cell Projection Organization Non-canonical Wnt Signaling Pathway Spindle Midzone Cytoskeleton-dependent Intracellular Transport G Protein Activity Cellular Response To CAMP Phosphoric Ester Hydrolase Activity Cellular Response To Raffinose Fructose 1,6-bisphosphate 1-phosphatase Activity Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Cell-cell Contact Zone Coreceptor-mediated Virion Attachment To Host Cell Cellular Anatomical Entity Morphogenesis Susceptibility To T Cell Mediated Cytotoxicity Sperm Mitochondrion Organization Mitochondrion Localization Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Neurotrophin Production Axon Cytoplasm Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Axonal Transport Anterograde Axonal Transport Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Antigen Processing And Presentation Following Phagocytosis Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Viral Exocytosis Regulation Of Plasma Membrane Bounded Cell Projection Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Organelle Transport Along Microtubule Regulation Of Cell Projection Organization Cellular Hypotonic Salinity Response Fusion Of Virus Membrane With Host Plasma Membrane Susceptibility To Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity	Identical Protein Binding Intermediate Filament Keratinization Epidermis Development Keratin Filament Cell Adhesion Mediator Activity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Tissue Development Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cell Adhesion Molecule Binding Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Regulation Of Leukocyte Mediated Cytotoxicity Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Mast Cell Activation Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Positive Regulation Of Immune Response To Tumor Cell Regulation Of Mast Cell Activation Adherens Junction Regulation Of Lymphocyte Mediated Immunity Negative Regulation Of Innate Immune Response Cell-cell Contact Zone Cochlea Morphogenesis Semicircular Canal Formation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Neuron Apoptotic Process Positive Regulation Of Mast Cell Activation By Fc-epsilon Receptor Signaling Pathway TRNA-dihydrouridine20 Synthase Activity L-cysteine Desulfurase Complex Symbiont Entry Into Host Cell Lymphocyte Mediated Immunity Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
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