CORO1B

Description		coronin 1B
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Focal Adhesion Lamellipodium Cell Leading Edge Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding Cadherin Binding Actin Filament Binding Arp2/3 Complex Binding
	Biological Process	Actin Filament Organization Cell Migration Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endothelial Cell Chemotaxis Cellular Response To Platelet-derived Growth Factor Stimulus Wound Healing Actin Filament Bundle Assembly Negative Regulation Of Cellular Component Organization Negative Regulation Of Smooth Muscle Cell Chemotaxis Actin Filament Branching Protein Localization To Cell Leading Edge Positive Regulation Of Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Non-response to citalopram or escitalopram and depression ( 27622933) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: ARPC2 FXR1 KPNA2 LHX4 POLR1C PRKCA SSH1 TERF1 TRIM15
Entrez ID		57175
HPRD ID		16743
Ensembl ID		ENSG00000172725
Uniprot IDs		Q9BR76
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytokine Production Regulation Of Cytokine Production Positive Regulation Of Macromolecule Metabolic Process Regulation Of Viral Life Cycle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Viral Penetration Into Host Nucleus Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cellular Component Organization Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Protein-containing Complex Assembly Positive Regulation Of Shelterin Complex Assembly Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Actin Filament Polymerization Muscle Cell Projection Membrane Cell Leading Edge Regulation Of AMPA Glutamate Receptor Clustering Positive Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Intracellular Transport Of Viral Material Mesodermal Cell Fate Determination Medial Motor Column Neuron Differentiation Nucleus Regulation Of Viral Process Positive Regulation Of Gene Expression Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Angiotensin-activated Signaling Pathway RNA Strand Annealing Activity Nuclear Pore Localization Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization To Telomere Fibrillar Center Shelterin Complex Negative Regulation Of Viral Life Cycle Desmosome Assembly
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