CABP1 and PPP3R1

Number of citations of the paper that reports this interaction (PubMedID 11108966)
0

Data Source:
BioGRID (pull down)

		CABP1	PPP3R1
Description		calcium binding protein 1	protein phosphatase 3 regulatory subunit B, alpha
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoplasm Golgi Apparatus Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Membrane Synapse Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Calcineurin Complex Protein Serine/threonine Phosphatase Complex Membrane Sarcolemma Synapse Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	Enzyme Inhibitor Activity Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Nuclear Localization Sequence Binding Metal Ion Binding Calcium-dependent Protein Binding	Phosphoprotein Phosphatase Activity Calcium-dependent Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Phosphatase Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Visual Perception Negative Regulation Of Protein Import Into Nucleus	Branching Involved In Blood Vessel Morphogenesis Epithelial To Mesenchymal Transition Protein Import Into Nucleus Heart Development Schwann Cell Development Myelination In Peripheral Nervous System Calcineurin-NFAT Signaling Cascade Protein Localization To Nucleus Positive Regulation Of Transcription By RNA Polymerase II Lung Epithelial Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Synaptic Vesicle Cycle Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Calcium Ion Import Across Plasma Membrane
Pathways		Sensory processing of sound by inner hair cells of the cochlea	Activation of BAD and translocation to mitochondria DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation
Drugs			Myristic acid Voclosporin
Diseases
GWAS		C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Chronotype ( 30696823) Serum metabolite levels ( 33031748) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 33536424)	General cognitive ability ( 29844566) Height ( 25282103) Hip index ( 34021172) Intelligence (MTAG) ( 29326435) Schizophrenia ( 30285260) Urinary potassium excretion ( 31409800)
Interacting Genes		9 interacting genes: CACNA1A CACNA1C CSNK2A2 FOS GRK5 ITPR1 ITPR3 NMT1 PPP3R1	12 interacting genes: CABP1 CABP2 CABP5 CHRNA6 MAP3K5 MYC NAP1L2 NFATC1 NFATC2 PPP3CA PPP3CC RCAN1
Entrez ID		9478	5534
HPRD ID		12025	03195
Ensembl ID		ENSG00000157782	ENSG00000221823
Uniprot IDs		C9J8G2 Q9NZU7	P63098
PDB IDs		2K7B 2K7C 2K7D 2LAN 2LAP 3OX5 3OX6	1AUI 1M63 1MF8 2P6B 3LL8 4F0Z 4OR9 4ORA 4ORC 5SVE 6NUC 6NUF 6NUU 7U0T 9B9G 9CHU 9CHV 9CHX
Enriched GO Terms of Interacting Partners?		Calcium Ion Transmembrane Import Into Cytosol Calcium Channel Activity Inositol 1,4,5-trisphosphate-gated Calcium Channel Activity Monoatomic Ion Channel Activity Calcium-mediated Signaling Calcium Ion Transmembrane Transport Calcineurin Complex Calcium Ion Transport Intracellularly Gated Calcium Channel Activity Platelet Dense Tubular Network Membrane Metal Ion Transport Inositol 1,4,5 Trisphosphate Binding High Voltage-gated Calcium Channel Activity Cytoplasm Monoatomic Cation Transport Regulation Of Sequestering Of Calcium Ion Calcium Ion Import Across Plasma Membrane Import Across Plasma Membrane Voltage-gated Calcium Channel Complex Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Import Into Cytosol Intracellular Signaling Cassette Monoatomic Ion Transport Voltage-gated Calcium Channel Activity Calcium Ion Import Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Transmembrane Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Transport Vesicle Membrane Phosphatase Binding Wnt Signaling Pathway Medium-term Memory Cellular Response To Prolactin Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Myristoyltransferase Activity Renal Phosphate Ion Absorption Inorganic Ion Transmembrane Transport Protein Homotetramerization Sarcoplasmic Reticulum Monoatomic Ion Transmembrane Transport Positive Regulation Of Establishment Of Protein Localization Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Signal Transduction Regulation Of Metal Ion Transport Cerebral Cortex Development	Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Calcium-mediated Signaling Negative Regulation Of Smooth Muscle Cell Differentiation Intracellular Signaling Cassette Myotube Cell Development Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Smooth Muscle Cell Differentiation Calmodulin-dependent Protein Phosphatase Activity Calcium Channel Regulator Activity Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Signal Transduction Striated Muscle Cell Development Negative Regulation Of Muscle Cell Differentiation Protein Serine/threonine Phosphatase Complex Positive Regulation Of Kidney Development Positive Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Muscle Cell Development Regulation Of Calcium-mediated Signaling Regulation Of Cell Differentiation Negative Regulation Of Calcium Ion Import Regulation Of Calcium Ion Import Across Plasma Membrane Positive Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Cell Differentiation Regulation Of Developmental Process Intracellular Signal Transduction Positive Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Regulation Of Muscle Cell Differentiation Regulation Of Kidney Development Negative Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Developmental Process Regulation Of Calcium Ion Import Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Negative Regulation Of Angiotensin-activated Signaling Pathway Negative Regulation Of Calcium Ion Transport Regulation Of Cell Proliferation Involved In Kidney Morphogenesis Axonemal Basal Plate Positive Regulation Of Calcium-mediated Signaling Calcium Ion Binding Positive Regulation Of Calcium Ion Transmembrane Transport Response To Ischemia Excitatory Postsynaptic Potential Negative Regulation Of Cation Transmembrane Transport
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