SYTL5 and RAB6A

Number of citations of the paper that reports this interaction (PMID 12051743)
12

Data Source:
HPRD (in vivo, in vitro)

		SYTL5	RAB6A
Gene Name		synaptotagmin-like 5	RAB6A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis	Protein Targeting To Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule
Pathways			Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: CEP70 RAB27A RAB27B RAB3A RAB6A WAC	20 interactors: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		94122	5870
HPRD ID		06736	01543
Ensembl ID		ENSG00000147041	ENSG00000175582
Uniprot IDs		Q8TDW5	P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Multivesicular Body Sorting Pathway Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Protein Secretion Regulation Of Exocytosis Small GTPase Mediated Signal Transduction Positive Regulation Of Regulated Secretory Pathway Establishment Of Vesicle Localization Vesicle Localization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Intracellular Protein Transport Melanosome Localization Regulation Of Regulated Secretory Pathway Establishment Of Organelle Localization Positive Regulation Of Secretion Exocytosis Regulation Of Vesicle-mediated Transport Cellular Pigmentation Organelle Localization Cellular Protein Localization Protein Transport Secretion By Cell Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of Constitutive Secretory Pathway Complement-dependent Cytotoxicity Histone H2B Conserved C-terminal Lysine Ubiquitination Synaptic Vesicle Transport Pigmentation Secretion Regulation Of Secretion Multivesicular Body Organization Cytotoxic T Cell Degranulation Intracellular Signal Transduction Positive Regulation Of Transport Protein Localization Establishment Of Localization In Cell Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Sensory Perception Of Touch	Protein Geranylgeranylation Protein Localization Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Prenylation Protein Transport Establishment Of Protein Localization Minus-end-directed Organelle Transport Along Microtubule Cellular Protein Localization Transport Retrograde Transport, Endosome To Golgi Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Vesicle-mediated Transport Microtubule-based Movement Positive Regulation Of Hydrolase Activity Microtubule-based Transport Protein Targeting To Golgi Cytoskeleton-dependent Intracellular Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Protein Targeting Organelle Assembly Protein Localization To Golgi Apparatus Endosomal Transport Protein Localization To Organelle Regulation Of Proteinase Activated Receptor Activity Epidermal Growth Factor Catabolic Process Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Testosterone Secretion Positive Regulation Of Catalytic Activity Organelle Transport Along Microtubule Intra-Golgi Vesicle-mediated Transport Microtubule Anchoring Rab Protein Signal Transduction Regulation Of Catalytic Activity Luteinizing Hormone Secretion Negative Regulation Of Phospholipase C Activity Positive Regulation Of Androgen Secretion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Establishment Of Protein Localization To Organelle Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Phagosome-lysosome Fusion Phagosome Acidification Negative Regulation Of Protein Targeting To Membrane
Tagcloud ?			autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Difference) ?			autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Intersection) ?