SYTL5 and CCDC85A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYTL5	CCDC85A
Description		synaptotagmin like 5	coiled-coil domain containing 85A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Exocytic Vesicle	Adherens Junction Anchoring Junction
	Molecular Function	Protein Binding Phospholipid Binding Zinc Ion Binding Small GTPase Binding Neurexin Family Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Copper levels ( 26025379) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Menarche (age at onset) ( 21102462 25231870) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Type 2 diabetes ( 26818947)
Interacting Genes		8 interacting genes: CCDC85A CEP70 RAB27A RAB3A RAB6A TRIM54 WAC YIF1A	5 interacting genes: PFDN1 STMN2 SYTL5 TMEM132D VPS26C
Entrez ID		94122	114800
HPRD ID		06736	19098
Ensembl ID		ENSG00000147041	ENSG00000055813
Uniprot IDs		Q8TDW5	Q96PX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Myosin V Binding Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Regulated Secretory Pathway GTPase Activity Synaptic Vesicle Transport GTP Binding Establishment Of Organelle Localization Evoked Neurotransmitter Secretion Peptidyl-cysteine Methylation Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Protein Localization To Extracellular Region Organelle Localization Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Vesicle-mediated Transport Regulated Exocytosis Positive Regulation Of Exocytosis Protein Transport Establishment Of Protein Localization To Extracellular Region Protein Secretion Vesicle Localization Regulation Of Dense Core Granule Exocytosis Secretory Granule Membrane Sensory Perception Of Touch Establishment Of Vesicle Localization Antigen Processing And Presentation Endosome To Plasma Membrane Transport Vesicle Complement-dependent Cytotoxicity Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Clathrin-sculpted Glutamate Transport Vesicle Membrane Minus-end-directed Organelle Transport Along Microtubule Exosomal Secretion Acrosomal Vesicle Exocytosis Clathrin-sculpted Monoamine Transport Vesicle Membrane Regulation Of Microtubule Cytoskeleton Organization Constitutive Secretory Pathway Protein Localization To Golgi Membrane Weibel-Palade Body Regulation Of Exocytosis Regulation Of Plasma Membrane Repair Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Natural Killer Cell Degranulation Establishment Of Localization In Cell Synaptic Vesicle Maturation Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Maintenance Of Presynaptic Active Zone Structure Exocytosis Presynaptic Active Zone Organization Protein Domain Specific Binding
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