SYTL4 and RAB8A

Number of citations of the paper that reports this interaction (PMID 11773082)
41

Data Source:
HPRD (in vitro, in vivo)

		SYTL4	RAB8A
Gene Name		synaptotagmin-like 4	RAB8A, member RAS oncogene family
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Centrosome Plasma Membrane Synaptic Vesicle Extrinsic Component Of Membrane Secretory Granule Transport Vesicle Membrane	Golgi Membrane Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Plasma Membrane Cilium Synaptic Vesicle Postsynaptic Density Trans-Golgi Network Transport Vesicle Dendrite Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Nonmotile Primary Cilium Ciliary Basal Body Neuronal Cell Body Phagocytic Vesicle Recycling Endosome Membrane Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Transporter Activity Phospholipid Binding Zinc Ion Binding Rab GTPase Binding Neurexin Family Protein Binding	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Organelle Organization Axonogenesis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Membrane Organization Protein Localization To Plasma Membrane
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium G2/M Transition Assembly of the primary cilium Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CCDC85B CEP70 FXR2 HMG20A INS RAB27A RAB27B RAB3A RAB8A STX1A STXBP1 ZBTB7B	20 interactors: BAG6 BIRC6 GDI2 MAP4K2 MDM2 MYO5B MYO5C OCRL ODF2 OPTN PDE6D PQBP1 RAB3IP RABIF RIMS2 RPH3A RPH3AL SYTL1 SYTL4 TFRC
Entrez ID		94121	4218
HPRD ID		06735	01296
Ensembl ID		ENSG00000102362
Uniprot IDs		A8K973 B2R7R4 Q71SF7 Q96C24	B4DEK7 P61006
PDB IDs		2CSZ 3FDW	3QBT 3TNF
Enriched GO Terms of Interacting Partners?		Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Regulation Of Exocytosis Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Localization Synaptic Vesicle Transport Establishment Of Organelle Localization Positive Regulation Of Secretion Exocytosis Regulation Of Secretion Regulation Of Vesicle-mediated Transport Rab Protein Signal Transduction Organelle Localization Secretion By Cell Regulation Of Cellular Localization Neurotransmitter Secretion Glutamate Secretion Secretion Protein Secretion Regulation Of Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Transport Regulation Of Synaptic Vesicle Transport Neurotransmitter Transport Multivesicular Body Sorting Pathway Cell-cell Signaling Synaptic Vesicle Exocytosis Vesicle Organization Acid Secretion Ras Protein Signal Transduction Regulation Of Neurotransmitter Secretion Synaptic Transmission Regulation Of Synaptic Vesicle Priming Dicarboxylic Acid Transport Regulation Of Synaptic Transmission Synaptic Vesicle Maturation Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Energy Reserve Metabolic Process Positive Regulation Of Regulated Secretory Pathway Intracellular Protein Transport Neuromuscular Synaptic Transmission Amino Acid Transport Regulation Of Synaptic Plasticity Melanosome Transport	Establishment Of Protein Localization Protein Localization Protein Transport Vesicle-mediated Transport Cellular Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Intracellular Transport Exocytosis Regulation Of Exocytosis Regulation Of Catalytic Activity Golgi To Plasma Membrane Transport Regulation Of Signaling Intracellular Signal Transduction Secretion By Cell Protein Localization To Organelle Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Protein Localization To Membrane Regulation Of Signal Transduction Cell Cycle Process Secretion Mitotic Cell Cycle Process Negative Regulation Of Signaling Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Transport Organelle Organization Post-Golgi Vesicle-mediated Transport Positive Regulation Of GTPase Activity Negative Regulation Of Proteolysis Mitotic Cell Cycle Protein Localization To Membrane Negative Regulation Of Protein Processing Traversing Start Control Point Of Mitotic Cell Cycle Multivesicular Body Sorting Pathway Negative Regulation Of Receptor Recycling Regulation Of Vesicle-mediated Transport Regulation Of GTPase Activity Response To Vitamin B1 Response To Ether Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Signal Transduction By P53 Class Mediator Cell Cycle Regulation Of Protein Processing G2/M Transition Of Mitotic Cell Cycle Membrane Organization Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity
Tagcloud ?		acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e plscr4 profoundly saponin slc27a3 triglycerides vldlr	apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular
Tagcloud (Difference) ?		acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e plscr4 profoundly saponin slc27a3 triglycerides vldlr	apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular
Tagcloud (Intersection) ?