RAB8A and MYO5C

Number of citations of the paper that reports this interaction (PMID 17507647)
52

Data Source:
BioGRID (two hybrid)

		RAB8A	MYO5C
Gene Name		RAB8A, member RAS oncogene family	myosin VC
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Plasma Membrane Cilium Synaptic Vesicle Postsynaptic Density Trans-Golgi Network Transport Vesicle Dendrite Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Nonmotile Primary Cilium Ciliary Basal Body Neuronal Cell Body Phagocytic Vesicle Recycling Endosome Membrane Extracellular Vesicular Exosome Primary Cilium	Myosin Complex Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding	Motor Activity Actin Binding Calmodulin Binding ATP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Organelle Organization Axonogenesis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Membrane Organization Protein Localization To Plasma Membrane	Metabolic Process
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium G2/M Transition Assembly of the primary cilium Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: BAG6 BIRC6 GDI2 MAP4K2 MDM2 MYO5B MYO5C OCRL ODF2 OPTN PDE6D PQBP1 RAB3IP RABIF RIMS2 RPH3A RPH3AL SYTL1 SYTL4 TFRC	3 interactors: IKBKG POT1 RAB8A
Entrez ID		4218	55930
HPRD ID		01296	11380
Ensembl ID			ENSG00000128833
Uniprot IDs		B4DEK7 P61006	Q9NQX4
PDB IDs		3QBT 3TNF
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Protein Localization Protein Transport Vesicle-mediated Transport Cellular Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Intracellular Transport Exocytosis Regulation Of Exocytosis Regulation Of Catalytic Activity Golgi To Plasma Membrane Transport Regulation Of Signaling Intracellular Signal Transduction Secretion By Cell Protein Localization To Organelle Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Protein Localization To Membrane Regulation Of Signal Transduction Cell Cycle Process Secretion Mitotic Cell Cycle Process Negative Regulation Of Signaling Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Transport Organelle Organization Post-Golgi Vesicle-mediated Transport Positive Regulation Of GTPase Activity Negative Regulation Of Proteolysis Mitotic Cell Cycle Protein Localization To Membrane Negative Regulation Of Protein Processing Traversing Start Control Point Of Mitotic Cell Cycle Multivesicular Body Sorting Pathway Negative Regulation Of Receptor Recycling Regulation Of Vesicle-mediated Transport Regulation Of GTPase Activity Response To Vitamin B1 Response To Ether Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Signal Transduction By P53 Class Mediator Cell Cycle Regulation Of Protein Processing G2/M Transition Of Mitotic Cell Cycle Membrane Organization Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity	Positive Regulation Of DNA Strand Elongation Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Fusion To Target Membrane Telomere Formation Via Telomerase Establishment Of Organelle Localization Telomere Capping Positive Regulation Of Helicase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Organelle Localization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Transferase Activity Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Telomere Maintenance Via Telomere Lengthening Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Long-term Neuronal Synaptic Plasticity B Cell Homeostasis NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Vesicle Fusion Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Synaptic Vesicle Exocytosis Regulation Of Neuronal Synaptic Plasticity I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Rab Protein Signal Transduction Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Vesicle Docking Involved In Exocytosis TRIF-dependent Toll-like Receptor Signaling Pathway Lymphocyte Homeostasis
Tagcloud ?		apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular
Tagcloud (Difference) ?		apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular
Tagcloud (Intersection) ?