RAB8A and RAB3IP

Number of citations of the paper that reports this interaction (PMID 12221131)
45

Data Source:
HPRD (two hybrid)

		RAB8A	RAB3IP
Gene Name		RAB8A, member RAS oncogene family	RAB3A interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Plasma Membrane Cilium Synaptic Vesicle Postsynaptic Density Trans-Golgi Network Transport Vesicle Dendrite Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Nonmotile Primary Cilium Ciliary Basal Body Neuronal Cell Body Phagocytic Vesicle Recycling Endosome Membrane Extracellular Vesicular Exosome Primary Cilium	Nucleus Centrosome Cytosol Cytoskeleton Lamellipodium Ciliary Basal Body
	Molecular Function	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Organelle Organization Axonogenesis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Membrane Organization Protein Localization To Plasma Membrane	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Organelle Organization Positive Regulation Of Rab GTPase Activity Protein Localization To Organelle Cilium Assembly
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium G2/M Transition Assembly of the primary cilium Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic	Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: BAG6 BIRC6 GDI2 MAP4K2 MDM2 MYO5B MYO5C OCRL ODF2 OPTN PDE6D PQBP1 RAB3IP RABIF RIMS2 RPH3A RPH3AL SYTL1 SYTL4 TFRC	19 interactors: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A ZNF410
Entrez ID		4218	117177
HPRD ID		01296	10565
Ensembl ID			ENSG00000127328
Uniprot IDs		B4DEK7 P61006	Q96QF0
PDB IDs		3QBT 3TNF
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Protein Localization Protein Transport Vesicle-mediated Transport Cellular Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Intracellular Transport Exocytosis Regulation Of Exocytosis Regulation Of Catalytic Activity Golgi To Plasma Membrane Transport Regulation Of Signaling Intracellular Signal Transduction Secretion By Cell Protein Localization To Organelle Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Protein Localization To Membrane Regulation Of Signal Transduction Cell Cycle Process Secretion Mitotic Cell Cycle Process Negative Regulation Of Signaling Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Transport Organelle Organization Post-Golgi Vesicle-mediated Transport Positive Regulation Of GTPase Activity Negative Regulation Of Proteolysis Mitotic Cell Cycle Protein Localization To Membrane Negative Regulation Of Protein Processing Traversing Start Control Point Of Mitotic Cell Cycle Multivesicular Body Sorting Pathway Negative Regulation Of Receptor Recycling Regulation Of Vesicle-mediated Transport Regulation Of GTPase Activity Response To Vitamin B1 Response To Ether Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Signal Transduction By P53 Class Mediator Cell Cycle Regulation Of Protein Processing G2/M Transition Of Mitotic Cell Cycle Membrane Organization Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity	Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Fusion To Target Membrane Protein Secretion Protein Localization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Ras Protein Signal Transduction Organelle Fusion Protein Transport Establishment Of Protein Localization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Regulated Secretory Pathway Membrane Fusion Organelle Localization Vesicle-mediated Transport Regulation Of Regulated Secretory Pathway Secretion By Cell Vesicle Organization Keratinization Skin Development Regulation Of Cellular Localization Vesicle Fusion Synaptic Transmission Organelle Organization Regulation Of Neuronal Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Small GTPase Mediated Signal Transduction Epidermis Development Secretion Positive Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Secretion N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Positive Regulation Of Transport Cellular Protein Localization Keratinocyte Differentiation Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane
Tagcloud ?		apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular	11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Difference) ?		apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular	11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Intersection) ?