NMT2 and ANXA7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		NMT2	ANXA7
Description		N-myristoyltransferase 2	annexin A7
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Host Cell	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Chromaffin Granule Membrane Extracellular Exosome
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity	Phosphatidylserine Binding RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding
	Biological Process	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Opsin-mediated Signaling Pathway Protein Localization To Membrane Intracellular Transport Of Virus	Autophagy Negative Regulation Of Gene Expression Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion Response To Phorbol 13-acetate 12-myristate
Pathways		Membrane binding and targetting of GAG proteins eNOS activation Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Copper levels ( 26025379)
Interacting Genes		14 interacting genes: ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ RBM11 SMN1 TK1 TMED9 TP53	109 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 HUNK INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		9397	310
HPRD ID		11948	01720
Ensembl ID		ENSG00000152465	ENSG00000138279
Uniprot IDs		B3KT39 O60551 Q5VUC6	B2R657 P20073
PDB IDs		4C2X 6PAU	8W5S
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus B Cell Lineage Commitment Leukocyte Apoptotic Process Glial Cell Apoptotic Process Nucleus Positive Regulation Of Neuron Apoptotic Process Response To Radiation Regulation Of Neuron Apoptotic Process Protein Tetramerization Identical Protein Binding Developmental Process Response To Metal Ion Negative Regulation Of Cell Population Proliferation Developmental Growth Molecular Function Activator Activity Positive Regulation Of Amyloid Precursor Protein Catabolic Process Protein Phosphatase 2A Binding Neuron Apoptotic Process T Cell Apoptotic Process B Cell Homeostasis Response To UV Release Of Cytochrome C From Mitochondria Response To Ionizing Radiation Protease Binding Response To Oxidative Stress Hematopoietic Stem Cell Differentiation Response To X-ray Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Neuron Maturation T Cell Lineage Commitment Positive Regulation Of Excitatory Postsynaptic Potential Vesicle Membrane Lymphocyte Apoptotic Process T Cell Homeostasis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Cell Fate Commitment Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of T Cell Apoptotic Process Regulation Of Glial Cell Proliferation Regulation Of Apoptotic Process Response To Nicotine T Cell Differentiation In Thymus Regulation Of Programmed Cell Death Cytoplasm Cellular Developmental Process Calcium-dependent Phospholipid Binding	TORC1 Signaling Extracellular Exosome TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of TORC1 Signaling Regulation Of TORC1 Signaling Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of TOR Signaling Positive Regulation Of Metabolic Process Positive Regulation Of TORC1 Signaling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Cytoplasm Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal Extracellular Matrix Positive Regulation Of Biosynthetic Process Positive Regulation Of TOR Signaling Developmental Process Regulation Of Metabolic Process Macromolecule Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Protein Deubiquitination Cellular Response To Nutrient Levels Regulation Of Proteolysis Histone H3T6 Kinase Activity Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Metabolic Process Platelet Alpha Granule Lumen Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Blood Microparticle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Cytoplasmic Translation Diacylglycerol-dependent Serine/threonine Kinase Activity Cytosol Nuclear Matrix Response To Interleukin-1 Response To Cytokine Regulation Of Protein Localization Negative Regulation Of Signal Transduction Calyx Of Held Negative Regulation Of Translational Initiation Protein Kinase C Signaling Proteasomal Protein Catabolic Process
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