NMT2

Description		N-myristoyltransferase 2
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Host Cell
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity
	Biological Process	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Opsin-mediated Signaling Pathway Protein Localization To Membrane Intracellular Transport Of Virus
Pathways		Membrane binding and targetting of GAG proteins eNOS activation Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		14 interacting genes: ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ RBM11 SMN1 TK1 TMED9 TP53
Entrez ID		9397
HPRD ID		11948
Ensembl ID		ENSG00000152465
Uniprot IDs		B3KT39 O60551 Q5VUC6
PDB IDs		4C2X 6PAU
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus B Cell Lineage Commitment Leukocyte Apoptotic Process Glial Cell Apoptotic Process Nucleus Positive Regulation Of Neuron Apoptotic Process Response To Radiation Regulation Of Neuron Apoptotic Process Protein Tetramerization Identical Protein Binding Developmental Process Response To Metal Ion Negative Regulation Of Cell Population Proliferation Developmental Growth Molecular Function Activator Activity Positive Regulation Of Amyloid Precursor Protein Catabolic Process Protein Phosphatase 2A Binding Neuron Apoptotic Process T Cell Apoptotic Process B Cell Homeostasis Response To UV Release Of Cytochrome C From Mitochondria Response To Ionizing Radiation Protease Binding Response To Oxidative Stress Hematopoietic Stem Cell Differentiation Response To X-ray Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Neuron Maturation T Cell Lineage Commitment Positive Regulation Of Excitatory Postsynaptic Potential Vesicle Membrane Lymphocyte Apoptotic Process T Cell Homeostasis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Cell Fate Commitment Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of T Cell Apoptotic Process Regulation Of Glial Cell Proliferation Regulation Of Apoptotic Process Response To Nicotine T Cell Differentiation In Thymus Regulation Of Programmed Cell Death Cytoplasm Cellular Developmental Process Calcium-dependent Phospholipid Binding
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