NMT2 and BTF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NMT2	BTF3
Description		N-myristoyltransferase 2	basic transcription factor 3
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Host Cell	Nucleus Cytoplasm Cytosol Nascent Polypeptide-associated Complex
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity	RNA Binding Protein Binding
	Biological Process	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Opsin-mediated Signaling Pathway Protein Localization To Membrane Intracellular Transport Of Virus	In Utero Embryonic Development Protein Transport Negative Regulation Of Protein Localization To Endoplasmic Reticulum
Pathways		Membrane binding and targetting of GAG proteins eNOS activation Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Eyebrow thickness ( 26926045) Monobrow thickness ( 26926045)
Interacting Genes		14 interacting genes: ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ RBM11 SMN1 TK1 TMED9 TP53	12 interacting genes: APP CDC42 CEBPA CSNK2B IFTAP MED21 NMT2 NOTO POLR2B TXLNA TXLNB ZDHHC17
Entrez ID		9397	689
HPRD ID		11948	03966
Ensembl ID		ENSG00000152465	ENSG00000145741
Uniprot IDs		B3KT39 O60551 Q5VUC6	P20290
PDB IDs		4C2X 6PAU	3LKX 3MCB 7QWQ 7QWR 9F1B 9F1C 9F1D 9FQ0
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus B Cell Lineage Commitment Leukocyte Apoptotic Process Glial Cell Apoptotic Process Nucleus Positive Regulation Of Neuron Apoptotic Process Response To Radiation Regulation Of Neuron Apoptotic Process Protein Tetramerization Identical Protein Binding Developmental Process Response To Metal Ion Negative Regulation Of Cell Population Proliferation Developmental Growth Molecular Function Activator Activity Positive Regulation Of Amyloid Precursor Protein Catabolic Process Protein Phosphatase 2A Binding Neuron Apoptotic Process T Cell Apoptotic Process B Cell Homeostasis Response To UV Release Of Cytochrome C From Mitochondria Response To Ionizing Radiation Protease Binding Response To Oxidative Stress Hematopoietic Stem Cell Differentiation Response To X-ray Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Neuron Maturation T Cell Lineage Commitment Positive Regulation Of Excitatory Postsynaptic Potential Vesicle Membrane Lymphocyte Apoptotic Process T Cell Homeostasis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Cell Fate Commitment Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of T Cell Apoptotic Process Regulation Of Glial Cell Proliferation Regulation Of Apoptotic Process Response To Nicotine T Cell Differentiation In Thymus Regulation Of Programmed Cell Death Cytoplasm Cellular Developmental Process Calcium-dependent Phospholipid Binding	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Interleukin-1 Cell Projection Morphogenesis Growth Cone Lamellipodium Neuron Projection Organization Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Amylin Binding Neuron Projection Morphogenesis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Peptide Positive Regulation Of Intracellular Signal Transduction Response To Cytokine Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of G Protein-coupled Receptor Internalization Macrophage Differentiation Endothelin Receptor Signaling Pathway Involved In Heart Process GBD Domain Binding Storage Vacuole Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Regulation Of DNA-templated Transcription Initiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Ribonucleoside Binding RNA-directed RNA Polymerase Activity RNA-templated Transcription DNA-directed RNA Polymerase Activity Prostaglandin-I Synthase Activity Glycylpeptide N-tetradecanoyltransferase Activity Protein Lipidation N-terminal Peptidyl-glycine N-myristoylation Peptidyl-lysine N6-myristoyltransferase Activity Positive Regulation Of Ribosome Biogenesis
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