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TGFBRAP1 and ACVR2B
Number of citations of the paper that reports this interaction (PubMedID
11278302
)
0
Data Source:
HPRD
(in vivo)
TGFBRAP1
ACVR2B
Description
transforming growth factor beta receptor associated protein 1
activin A receptor type 2B
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Early Endosome
Endomembrane System
Membrane
CORVET Complex
Cytoplasm
Plasma Membrane
Membrane
Protein-containing Complex
Receptor Complex
Activin Receptor Complex
Molecular Function
Transforming Growth Factor Beta Receptor Binding
Protein Binding
SMAD Binding
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Activin Receptor Activity, Type II
Transferase Activity
Activin Receptor Activity
Kinase Activator Activity
Growth Factor Binding
Metal Ion Binding
Activin Binding
Biological Process
Regulation Of DNA-templated Transcription
Intracellular Protein Transport
Autophagy
Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
Endosome To Lysosome Transport
Protein Transport
Vesicle-mediated Transport
Endosomal Vesicle Fusion
Regulation Of SNARE Complex Assembly
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal System Development
Gastrulation With Mouth Forming Second
Kidney Development
Lymphangiogenesis
Blood Vessel Remodeling
Regulation Of DNA-templated Transcription
Intracellular Iron Ion Homeostasis
Signal Transduction
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Determination Of Left/right Symmetry
Pattern Specification Process
Mesoderm Development
Heart Development
Response To Glucose
Post-embryonic Development
Anterior/posterior Pattern Specification
Regulation Of Signal Transduction
Insulin Secretion
Negative Regulation Of Ossification
Lung Development
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Pancreas Development
Developmental Process
Activin Receptor Signaling Pathway
Positive Regulation Of Activin Receptor Signaling Pathway
Organ Growth
Odontogenesis Of Dentin-containing Tooth
Positive Regulation Of Osteoblast Differentiation
Embryonic Foregut Morphogenesis
Skeletal System Morphogenesis
Roof Of Mouth Development
Lymphatic Endothelial Cell Differentiation
Artery Development
Venous Blood Vessel Development
Retina Vasculature Development In Camera-type Eye
Trophoblast Cell Migration
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Adipose Tissue Development
Pathways
Signaling by NODAL
Regulation of signaling by NODAL
Signaling by Activin
Signaling by Activin
Signaling by BMP
Drugs
Diseases
Heterotaxy; Situs ambiguus
GWAS
AIDS (
19754311
)
Body mass index (
26426971
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Gut microbiota relative abundance (Coprococcus) (
33208821
)
Menarche (age at onset) (
27182965
)
Obesity-related traits (
23251661
)
Preeclampsia (
23551011
)
Walking pace (
33128006
)
Bitter beverage consumption (
31046077
)
Body size at age 10 (
32376654
)
Estimated glomerular filtration rate (
31015462
31152163
)
P wave duration (
24850809
)
Interacting Genes
9 interacting genes:
ACVR1B
ACVR2B
ACVRL1
ALOX5
BMPR1A
SMAD2
SMAD4
TGFBR1
TGFBR2
26 interacting genes:
ACVR1B
BMP10
BMP2
BMP7
CRIPTO
DLG1
ERBIN
FBXO7
GDF11
GDF2
GDF5
IGSF1
INHBA
INHBB
INHBC
MSTN
NHERF2
NODAL
SCRIB
SNTB1
SNX1
SNX2
SNX27
SNX6
SYNJ2BP
TGFBRAP1
Entrez ID
9392
93
HPRD ID
06948
04106
Ensembl ID
ENSG00000135966
ENSG00000114739
Uniprot IDs
Q8WUH2
Q13705
PDB IDs
2H62
2QLU
4FAO
5NGV
5NHR
7MRZ
7OLY
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Activin Receptor Signaling Pathway
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Binding
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Activin Binding
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Response To Growth Factor
Roof Of Mouth Development
Activin Receptor Complex
Activin Receptor Activity, Type I
Transforming Growth Factor Beta Receptor Signaling Pathway
In Utero Embryonic Development
Chordate Embryonic Development
Positive Regulation Of SMAD Protein Signal Transduction
Embryo Development Ending In Birth Or Egg Hatching
Multicellular Organism Development
Cellular Response To Growth Factor Stimulus
I-SMAD Binding
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of SMAD Protein Signal Transduction
Endocardial Cushion Morphogenesis
Positive Regulation Of Developmental Process
Transforming Growth Factor Beta Receptor Activity, Type I
Positive Regulation Of Cell Differentiation
Heart Development
Regionalization
Negative Regulation Of Developmental Process
Regulation Of Cell Differentiation
Regulation Of Ossification
Trophoblast Cell Migration
Ventricular Septum Morphogenesis
Positive Regulation Of Multicellular Organismal Process
Transforming Growth Factor Beta Receptor Activity
Gastrulation
Anterior/posterior Pattern Specification
Mesoderm Development
Protein Serine/threonine Kinase Activity
Pattern Specification Process
Positive Regulation Of Epithelial To Mesenchymal Transition
Cell Surface Receptor Signaling Pathway
Tissue Morphogenesis
Artery Morphogenesis
Secondary Palate Development
Embryonic Morphogenesis
Receptor Complex
Anatomical Structure Formation Involved In Morphogenesis
Response To Transforming Growth Factor Beta
Cardiac Septum Morphogenesis
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Growth Factor Activity
Activin Receptor Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Cytokine Activity
Positive Regulation Of SMAD Protein Signal Transduction
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Cartilage Development
Regulation Of Signaling
Regulation Of Signal Transduction
BMP Signaling Pathway
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Developmental Process
Anatomical Structure Morphogenesis
Retromer, Tubulation Complex
Regulation Of Cell Communication
Retromer Complex
Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Differentiation
Regulation Of Intracellular Signal Transduction
Regulation Of Developmental Process
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Extracellular Space
Regulation Of Cartilage Development
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Signal Transduction
Signaling Receptor Binding
Regulation Of Multicellular Organismal Process
Tissue Morphogenesis
Regulation Of Cell Differentiation
Morphogenesis Of A Branching Structure
Cellular Response To Growth Factor Stimulus
Regulation Of Locomotion
Tube Morphogenesis
Regulation Of Reproductive Process
Response To Growth Factor
Animal Organ Development
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Multicellular Organismal Development
Cartilage Development
Morphogenesis Of An Epithelium
Extracellular Region
Nodal Signaling Pathway
Mesoderm Formation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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