TGFBRAP1

Description		transforming growth factor beta receptor associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Endomembrane System Membrane CORVET Complex
	Molecular Function	Transforming Growth Factor Beta Receptor Binding Protein Binding SMAD Binding
	Biological Process	Regulation Of DNA-templated Transcription Intracellular Protein Transport Autophagy Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly
Pathways
Drugs
Diseases
GWAS		AIDS ( 19754311) Body mass index ( 26426971) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Gut microbiota relative abundance (Coprococcus) ( 33208821) Menarche (age at onset) ( 27182965) Obesity-related traits ( 23251661) Preeclampsia ( 23551011) Walking pace ( 33128006)
Novel Interacting Genes		1 novel interacting genes: EIF4E2
Interacting Genes		9 interacting genes: ACVR1B ACVR2B ACVRL1 ALOX5 BMPR1A SMAD2 SMAD4 TGFBR1 TGFBR2
Entrez ID		9392
HPRD ID		06948
Ensembl ID		ENSG00000135966
Uniprot IDs		Q8WUH2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Activity Activin Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Activin Binding Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Response To Growth Factor Roof Of Mouth Development Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Signaling Pathway In Utero Embryonic Development Chordate Embryonic Development Positive Regulation Of SMAD Protein Signal Transduction Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Cellular Response To Growth Factor Stimulus I-SMAD Binding Enzyme-linked Receptor Protein Signaling Pathway Regulation Of SMAD Protein Signal Transduction Endocardial Cushion Morphogenesis Positive Regulation Of Developmental Process Transforming Growth Factor Beta Receptor Activity, Type I Positive Regulation Of Cell Differentiation Heart Development Regionalization Negative Regulation Of Developmental Process Regulation Of Cell Differentiation Regulation Of Ossification Trophoblast Cell Migration Ventricular Septum Morphogenesis Positive Regulation Of Multicellular Organismal Process Transforming Growth Factor Beta Receptor Activity Gastrulation Anterior/posterior Pattern Specification Mesoderm Development Protein Serine/threonine Kinase Activity Pattern Specification Process Positive Regulation Of Epithelial To Mesenchymal Transition Cell Surface Receptor Signaling Pathway Tissue Morphogenesis Artery Morphogenesis Secondary Palate Development Embryonic Morphogenesis Receptor Complex Anatomical Structure Formation Involved In Morphogenesis Response To Transforming Growth Factor Beta Cardiac Septum Morphogenesis
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