TGFBRAP1

Gene Name		transforming growth factor, beta receptor associated protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane
	Molecular Function	Small GTPase Regulator Activity Transforming Growth Factor Beta Receptor Binding Protein Binding SMAD Binding
	Biological Process	Regulation Of Transcription, DNA-templated Intracellular Protein Transport Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Vesicle-mediated Transport Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		AIDS ( 19754311) Obesity-related traits ( 23251661) Preeclampsia ( 23551011)
Protein-protein Interactions		9 interactors: ACVR1B ACVR2B ACVRL1 ALOX5 BMPR1A SMAD2 SMAD4 TGFBR1 TGFBR2
Entrez ID		9392
HPRD ID		06948
Ensembl ID		ENSG00000135966
Uniprot IDs		Q8WUH2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Activin Receptor Signaling Pathway Palate Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway In Utero Embryonic Development Signal Transduction By Phosphorylation Embryo Development Positive Regulation Of Protein Phosphorylation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Cardiovascular System Development Gastrulation Regulation Of Cell Differentiation Positive Regulation Of Protein Modification Process Positive Regulation Of SMAD Protein Import Into Nucleus Pattern Specification Process Tissue Development Heart Development Regulation Of SMAD Protein Import Into Nucleus BMP Signaling Pathway Regulation Of Protein Phosphorylation Intracellular Signal Transduction Epithelium Development Anterior/posterior Pattern Specification Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Protein Metabolic Process Response To Growth Factor Embryonic Morphogenesis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Phosphorylation Tube Development Response To Cholesterol Protein Phosphorylation Regulation Of Activin Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Mesoderm Development Positive Regulation Of Cellular Metabolic Process Tube Morphogenesis Positive Regulation Of BMP Signaling Pathway Regulation Of Signal Transduction
Tagcloud ?		500k 9x10 affymetrix agp alleles anril atherosclerosis cad camta1 conjoint depth genotyping german highlighted illumina immunochip largest loci periodontitis plasminogen plg replicated rs2679895 rs4252120 sets shared vamp3 worldwide