MMGT1 and STX6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MMGT1	STX6
Description		membrane magnesium transporter 1	syntaxin 6
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Early Endosome Membrane EMC Complex	Golgi Membrane Nucleoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Clathrin-coated Vesicle Synaptic Vesicle Membrane Organelle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Protein Binding Cobalt Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Monoatomic Cation Transport Cobalt Ion Transport Copper Ion Transport Iron Ion Transport Magnesium Ion Transport Iron Ion Transmembrane Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport	Intracellular Protein Transport Vesicle Fusion Endosome Organization Protein Transport Synaptic Vesicle To Endosome Fusion Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking
Pathways		Miscellaneous transport and binding events	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Creutzfeldt-Jakob disease (sporadic) ( 32949544) Intralaminar thalamic nuclei volume ( 34006833) Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 21685912 30089514) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		50 interacting genes: ADGRE2 AGR3 ANKRD46 APP ARLN C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MS4A13 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC33A2 SLC35B4 SLC35E4 SLC38A7 SLC61A1 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A	33 interacting genes: AQP6 ARMC8 DNAJC5 EBP EEA1 FAM210B GOLM2 GOPC LIME1 LMNA MARCHF2 MEOX2 MMGT1 MTERF2 MTIF3 NAPB PSMA3 PTPN9 SCN3B SNAP23 SNAP29 STOM STX16 STX1A STX2 STX7 TIMMDC1 TMEM14B TMEM205 TMEM86B VAMP4 VPS11 VPS18
Entrez ID		93380	10228
HPRD ID		06626	07231
Ensembl ID		ENSG00000169446	ENSG00000135823
Uniprot IDs		Q8N4V1	O43752
PDB IDs		6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V	2NPS 4J2C
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Membrane Docking Vesicle Docking SNARE Binding Organelle Localization By Membrane Tethering Membrane Fusion Vesicle Fusion Organelle Membrane Fusion Endoplasmic Reticulum Organelle Fusion Protein Binding Endoplasmic Reticulum Membrane Endomembrane System Membrane Organization Intracellular Transport Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Spontaneous Synaptic Transmission Intracellular Protein Transport Other Organism Cell Membrane Membrane Attack Complex Chloride Channel Inhibitor Activity Establishment Of Protein Localization Vesicle Organization Modulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Vesicle Priming Peroxisome Fission Complement Activation, GZMK Pathway Synaptic Vesicle Docking Astrocyte Projection Transmembrane Transporter Complex Recycling Endosome Mitochondrial Fission Macrophage Activation Positive Regulation Of Synaptic Transmission Complement Activation, Alternative Pathway Protein Transport Cellular Localization Establishment Of Localization In Cell	Organelle Fusion Vesicle Fusion Organelle Membrane Fusion SNARE Complex Syntaxin Binding Membrane Fusion SNAP Receptor Activity Organelle Localization By Membrane Tethering Vesicle Organization Membrane Docking Vesicle Docking Vesicle-mediated Transport Membrane Organization Cytoplasmic Vesicle Establishment Of Protein Localization Protein Transport Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Organelle Localization Cellular Localization Establishment Of Localization In Cell Synaptic Vesicle Membrane Organization Membrane SNARE Binding Intracellular Transport Synaptic Vesicle To Endosome Fusion Intracellular Protein Localization Endosome Organization Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Exocytosis Localization Within Membrane Vesicle Docking Involved In Exocytosis Lysosomal Membrane ATP-dependent Protein Binding Chloride Channel Inhibitor Activity CORVET Complex Azurophil Granule Membrane Endomembrane System Regulation Of Synaptic Vesicle Priming Azurophil Granule SNARE Complex Assembly Regulation Of Protein Localization Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway HOPS Complex Endocytic Vesicle Early Endosome Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Vesicle Targeting
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?