MMGT1 and TMEM60

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MMGT1	TMEM60
Description		membrane magnesium transporter 1	transmembrane protein 60
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Early Endosome Membrane EMC Complex	Membrane
	Molecular Function	Protein Binding Cobalt Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity	Protein Binding
	Biological Process	Monoatomic Cation Transport Cobalt Ion Transport Copper Ion Transport Iron Ion Transport Magnesium Ion Transport Iron Ion Transmembrane Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS			Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 30604766 31152163 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 26831199 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
Interacting Genes		50 interacting genes: ADGRE2 AGR3 ANKRD46 APP ARLN C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MS4A13 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC33A2 SLC35B4 SLC35E4 SLC38A7 SLC61A1 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A	91 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ARL13B ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC35H1 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21
Entrez ID		93380	85025
HPRD ID		06626	12923
Ensembl ID		ENSG00000169446	ENSG00000135211
Uniprot IDs		Q8N4V1	Q9H2L4
PDB IDs		6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Membrane Docking Vesicle Docking SNARE Binding Organelle Localization By Membrane Tethering Membrane Fusion Vesicle Fusion Organelle Membrane Fusion Endoplasmic Reticulum Organelle Fusion Protein Binding Endoplasmic Reticulum Membrane Endomembrane System Membrane Organization Intracellular Transport Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Spontaneous Synaptic Transmission Intracellular Protein Transport Other Organism Cell Membrane Membrane Attack Complex Chloride Channel Inhibitor Activity Establishment Of Protein Localization Vesicle Organization Modulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Vesicle Priming Peroxisome Fission Complement Activation, GZMK Pathway Synaptic Vesicle Docking Astrocyte Projection Transmembrane Transporter Complex Recycling Endosome Mitochondrial Fission Macrophage Activation Positive Regulation Of Synaptic Transmission Complement Activation, Alternative Pathway Protein Transport Cellular Localization Establishment Of Localization In Cell	Membrane Transmembrane Transport Protein Binding Monoatomic Ion Transport Plasma Membrane Basolateral Plasma Membrane Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Endoplasmic Reticulum Membrane Transport Vesicle Membrane Monoatomic Ion Transmembrane Transport Endoplasmic Reticulum Antiporter Activity Metal Ion Transport Organic Anion Transport Inorganic Cation Transmembrane Transport Inorganic Anion Transmembrane Transport Cytoplasmic Vesicle Zinc Export Across Plasma Membrane Inorganic Anion Transport Monoatomic Cation Transmembrane Transport Connexin Complex Chloride Transmembrane Transport Gap Junction Channel Activity Regulation Of PH Symporter Activity Neurotransmitter Transport Zinc Ion Import Into Lysosome Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Carbon Dioxide Transmembrane Transporter Activity Chloride Transport Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Clathrin-sculpted Monoamine Transport Vesicle Membrane Zinc Ion Transmembrane Transporter Activity Lysosomal Lumen Acidification Gap Junction Zinc Ion Transmembrane Transport Transmembrane Transporter Activity Zinc Ion Transport Gap Junction-mediated Intercellular Transport Sodium Ion Transport Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Amino Acid Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Proton-transporting V-type ATPase Complex Assembly
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