TRIP11 and THRA

Number of citations of the paper that reports this interaction (PMID 9256431)
19

Data Source:
BioGRID (pull down)

		TRIP11	THRA
Gene Name		thyroid hormone receptor interactor 11	thyroid hormone receptor, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleus Golgi Apparatus Cis-Golgi Network Cytoskeleton	Nucleus Nucleoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding	Steroid Receptor RNA Activator RNA Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Thyroid Hormone Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding TBP-class Protein Binding Protein Domain Specific Binding Chromatin DNA Binding Protein Complex Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Binding
	Biological Process	Protein Targeting To Golgi Ventricular Septum Development Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Nucleic Acid-templated Transcription	Cartilage Condensation Ossification Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Learning Or Memory Regulation Of Heart Contraction Female Courtship Behavior Response To Cold Hormone-mediated Signaling Pathway Gene Expression Positive Regulation Of Myotube Differentiation Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Erythrocyte Differentiation Intracellular Receptor Signaling Pathway Thyroid Gland Development Regulation Of Myeloid Cell Apoptotic Process Cytoplasmic Sequestering Of Transcription Factor Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Female Receptivity Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Catabolic Process Type I Pneumocyte Differentiation Negative Regulation Of DNA-templated Transcription, Initiation
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport	Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs			Liothyronine Levothyroxine Dextrothyroxine Liotrix 3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid
Diseases
GWAS		Height ( 20881960 18391950 18391951)	White blood cell count ( 21738480)
Protein-Protein Interactions		5 interactors: ARNT ATXN1L PSMC5 RB1 THRA	56 interactors: AKAP13 AMOTL2 ARID5A BTG1 BUB3 C1D CCND1 CDK7 CLIC1 COPS2 CREB1 CREBBP CUL1 DAP3 ESR1 FOXJ1 FUS GRIP1 GTF2B HDAC2 HDAC3 ITGB3BP L3MBTL3 MED1 MED21 MED25 MEF2A NCOA1 NCOA6 NCOR1 NCOR2 NR0B2 NR2F1 NRIP1 NSD1 OASL PML POU2F1 PRKDC PTGES3 RANBP9 RGN RXRA RXRB RXRG SEPP1 SLC16A2 SRC SUV39H1 TBL1X TDG TRIM24 TRIP11 YWHAH YWHAQ ZBTB3
Entrez ID		9321	7067
HPRD ID		05143	07185
Ensembl ID		ENSG00000100815	ENSG00000126351
Uniprot IDs		B2RUT2 Q15643 Q6MZL5	P10827 Q6FH41
PDB IDs			1NAV 2H77 2H79 3HZF 3ILZ 3JZB
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Erythrocyte Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Erythrocyte Homeostasis Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Tube Development Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Myeloid Cell Homeostasis Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Maintenance Of Protein Location In Cell Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Maintenance Of Protein Location Regulation Of Gene Expression Maintenance Of Location In Cell Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Sister Chromatid Biorientation Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Nitrogen Compound Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Differentiation Mitotic Cell Cycle Checkpoint	Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Rhythmic Process Organ Development Multicellular Organismal Development Regulation Of Cellular Process Anatomical Structure Development Developmental Process Cellular Response To Organic Substance Signal Transduction Chromosome Organization Signaling System Development
Tagcloud ?		14q32 5q31 5q33 apart apl aspirate break complication cytogenetic cytogenetics exon firstly fusion infrequent kiaa1509 myeloid neoplasm neoplasms partner pdgfrb promyelocytic q32 q33 rara rarely rearrangement rt undetectable xy	accounts averages bimodality bxd bxh chr counted encode ganglion heritable hoxb idea inbred krt1 lod mapped neuregulin nnc1 opposed qtl qtls retina retinal striking subsidiary surprisingly thyroxine trait vertebrate
Tagcloud (Difference) ?		14q32 5q31 5q33 apart apl aspirate break complication cytogenetic cytogenetics exon firstly fusion infrequent kiaa1509 myeloid neoplasm neoplasms partner pdgfrb promyelocytic q32 q33 rara rarely rearrangement rt undetectable xy	accounts averages bimodality bxd bxh chr counted encode ganglion heritable hoxb idea inbred krt1 lod mapped neuregulin nnc1 opposed qtl qtls retina retinal striking subsidiary surprisingly thyroxine trait vertebrate
Tagcloud (Intersection) ?