ITGB1BP1 and KRIT1

Number of citations of the paper that reports this interaction (PMID 11741838)
42

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		ITGB1BP1	KRIT1
Gene Name		integrin beta 1 binding protein 1	KRIT1, ankyrin repeat containing
Image
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Membrane Lamellipodium Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery	Extracellular Space Cytoplasm Microtubule Plasma Membrane Cell-cell Junction
	Molecular Function	GDP-dissociation Inhibitor Activity Integrin Binding Protein Binding Protein Transporter Activity Protein Kinase Binding Protein Complex Binding	Small GTPase Regulator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Microtubule Binding Protein Complex Binding
	Biological Process	Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Cell-matrix Adhesion Notch Signaling Pathway Integrin-mediated Signaling Pathway Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Fibroblast Migration Protein Transport Cell Migration Cell Differentiation Biomineral Tissue Development Negative Regulation Of Protein Binding Activation Of Protein Kinase B Activity Integrin Activation Regulation Of Cell Adhesion Mediated By Integrin Tube Formation Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of Cdc42 GTPase Activity Receptor Clustering Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Blood Vessel Size Myoblast Migration Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Cell Division Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of Protein Targeting To Membrane Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Integrin-mediated Signaling Pathway	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Small GTPase Mediated Signal Transduction Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Positive Regulation Of Protein Binding Cell Redox Homeostasis Regulation Of Catalytic Activity Regulation Of Establishment Of Cell Polarity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP CAMK2A EEF1A1 FAF1 FIGNL1 ITGB1 KRIT1 LRP1 LRP2 LRP8	6 interactors: FAS ITGB1BP1 PLCB3 RAP1A RGS4 TRPV4
Entrez ID		9270	889
HPRD ID		06194	05020
Ensembl ID		ENSG00000119185	ENSG00000001631
Uniprot IDs		B4DQY5 O14713	A4D1F7 O00522
PDB IDs		1K11 4DX8 4DX9 4JIF	3U7D 4DX8 4DXA 4HDO 4HDQ 4JIF
Enriched GO Terms of Interacting Partners?		Response To Radiation Response To Abiotic Stimulus Response To Light Stimulus Phototransduction, Visible Light Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Regulation Of Apoptotic Process Detection Of Light Stimulus Regulation Of Cell Death Isoprenoid Metabolic Process Detection Of Abiotic Stimulus Regulation Of Signaling Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Stimulus Endocytosis Steroid Metabolic Process Brain Development Cellular Response To Ionizing Radiation Regulation Of Metabolic Process Head Development Visual Learning Visual Behavior Regulation Of Protein Tyrosine Kinase Activity Alcohol Metabolic Process Receptor-mediated Endocytosis Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Ammon Gyrus Development Beta-amyloid Clearance Associative Learning Response To External Stimulus Central Nervous System Development Response To Stimulus Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Cell Death Developmental Cell Growth Negative Regulation Of Intracellular Signal Transduction Blood Vessel Morphogenesis Blood Coagulation Hemostasis Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Forebrain Development Synaptic Growth At Neuromuscular Junction Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Signaling Blood Vessel Development Cholesterol Metabolic Process	Regulation Of Cell Junction Assembly Positive Regulation Of Catalytic Activity Cortical Microtubule Organization Osmosensory Signaling Pathway Regulation Of Cell Differentiation Regulation Of MAPK Cascade Vasopressin Secretion Motor Neuron Apoptotic Process Energy Reserve Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of MAPK Cascade Regulation Of GTPase Activity Regulation Of Kinase Activity Regulation Of Cell Development Regulation Of Protein Metabolic Process Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Positive Regulation Of Microtubule Depolymerization Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Kinase Activity Response To Mechanical Stimulus Regulation Of Catalytic Activity Negative Regulation Of Kinase Activity Negative Regulation Of Protein Targeting To Membrane Necroptotic Signaling Pathway Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Protein Complex Assembly Positive Regulation Of Hydrolase Activity Regulation Of Protein Phosphorylation Integrin Activation Transformed Cell Apoptotic Process Activation-induced Cell Death Of T Cells Negative Regulation Of Fibroblast Migration Myoblast Migration Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Response To Osmotic Stress Positive Regulation Of Cellular Protein Metabolic Process Activation Of Protein Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Hyperosmotic Salinity Response Inflammatory Cell Apoptotic Process Negative Regulation Of Signaling Regulation Of Signal Transduction Cellular Response To Hyperoxia Positive Regulation Of Protein Homooligomerization Rap Protein Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Transferase Activity
Tagcloud ?			abstract assisted bm desorption flight foxo1 h2o2 hbm immunoblot improves ionization krev maldi migratory modulates modulator mscs pretreated protects proteomic qpcr rap1 ros sod2 tof trapped trophic valproic vpa
Tagcloud (Difference) ?			abstract assisted bm desorption flight foxo1 h2o2 hbm immunoblot improves ionization krev maldi migratory modulates modulator mscs pretreated protects proteomic qpcr rap1 ros sod2 tof trapped trophic valproic vpa
Tagcloud (Intersection) ?