KRIT1

Gene Name		KRIT1, ankyrin repeat containing
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Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Microtubule Plasma Membrane Cell-cell Junction
	Molecular Function	Small GTPase Regulator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Microtubule Binding Protein Complex Binding
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Small GTPase Mediated Signal Transduction Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Positive Regulation Of Protein Binding Cell Redox Homeostasis Regulation Of Catalytic Activity Regulation Of Establishment Of Cell Polarity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: FAS ITGB1BP1 PLCB3 RAP1A RGS4 TRPV4
Entrez ID		889
HPRD ID		05020
Ensembl ID		ENSG00000001631
Uniprot IDs		A4D1F7 O00522
PDB IDs		3U7D 4DX8 4DXA 4HDO 4HDQ 4JIF
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Junction Assembly Positive Regulation Of Catalytic Activity Cortical Microtubule Organization Osmosensory Signaling Pathway Regulation Of Cell Differentiation Regulation Of MAPK Cascade Vasopressin Secretion Motor Neuron Apoptotic Process Energy Reserve Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of MAPK Cascade Regulation Of GTPase Activity Regulation Of Kinase Activity Regulation Of Cell Development Regulation Of Protein Metabolic Process Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Positive Regulation Of Microtubule Depolymerization Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Kinase Activity Response To Mechanical Stimulus Regulation Of Catalytic Activity Negative Regulation Of Kinase Activity Negative Regulation Of Protein Targeting To Membrane Necroptotic Signaling Pathway Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Protein Complex Assembly Positive Regulation Of Hydrolase Activity Regulation Of Protein Phosphorylation Integrin Activation Transformed Cell Apoptotic Process Activation-induced Cell Death Of T Cells Negative Regulation Of Fibroblast Migration Myoblast Migration Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Response To Osmotic Stress Positive Regulation Of Cellular Protein Metabolic Process Activation Of Protein Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Hyperosmotic Salinity Response Inflammatory Cell Apoptotic Process Negative Regulation Of Signaling Regulation Of Signal Transduction Cellular Response To Hyperoxia Positive Regulation Of Protein Homooligomerization Rap Protein Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Transferase Activity
Tagcloud ?		abstract assisted bm desorption flight foxo1 h2o2 hbm immunoblot improves ionization krev maldi migratory modulates modulator mscs pretreated protects proteomic qpcr rap1 ros sod2 tof trapped trophic valproic vpa