AP5B1 and PDLIM7

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AP5B1	PDLIM7
Gene Name		adaptor-related protein complex 5, beta 1 subunit	PDZ and LIM domain 7 (enigma)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane AP-type Membrane Coat Adaptor Complex	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Protein Transport Endosomal Transport	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CALCOCO2 CAMK2B KCNRG NIF3L1 PDLIM7	34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		91056	9260
HPRD ID		13223	10436
Ensembl ID			ENSG00000196923
Uniprot IDs		Q2VPB7	Q9NR12
PDB IDs			2Q3G
Enriched GO Terms of Interacting Partners?		Inhibitory G-protein Coupled Receptor Phosphorylation Negative Regulation Of Delayed Rectifier Potassium Channel Activity Activation Of Meiosis Involved In Egg Activation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Response To Interferon-gamma Dihydrobiopterin Metabolic Process Activation Of Meiosis Regulation Of Synaptic Transmission, Cholinergic Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Skeletal Muscle Adaptation Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Synapse Structural Plasticity Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Egg Activation Regulation Of Synapse Maturation Negative Regulation Of Cation Channel Activity Negative Regulation Of Potassium Ion Transport Positive Regulation Of Dendritic Spine Development Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Cellular Response To Heat Regulation Of Ion Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
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