CC2D1A and CHMP4A

Number of citations: 0 (PubMedID 16730941)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		CC2D1A	CHMP4A
Name		coiled-coil and C2 domain containing 1A	charged multivesicular body protein 4A
Structure		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Endosome Membrane Membrane Ciliary Basal Body Synapse Extracellular Exosome Glutamatergic Synapse	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Multivesicular Body Membrane Amphisome Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Cadherin Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Endosome Organization Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Respiratory Gaseous Exchange Dendrite Arborization Apical Dendrite Arborization Regulation Of Postsynapse Assembly Negative Regulation Of SnRNA Transcription By RNA Polymerase II	Plasma Membrane Repair Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Membrane Invagination Protein Transport Macroautophagy Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding From Plasma Membrane Nervous System Process Protein Polymerization Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Plasma Membrane Tubulation Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport
Pathways		None	Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: GCH1
Interacting Genes		6 interacting genes: CDC37 CEBPA CHMP4A CHMP4C KLHL20 LRP1	14 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 NTAQ1 NUTF2 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		54862	29082
HPRD ID		08616	16597
Ensembl ID		ENSG00000132024	ENSG00000254505
Uniprot IDs		Q6P1N0	Q9BY43
PDB IDs		Not available	3C3O 5MK1
GO Terms Enriched among Interactors		Lysosomal Transport ESCRT III Complex Viral Budding From Plasma Membrane Amphisome Membrane Lysosomal Membrane Organization Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Establishment Of Protein Localization Vacuolar Transport Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Plasma Membrane Repair Mitotic Cytokinetic Process Multivesicular Body Membrane Viral Budding Nuclear Membrane Reassembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Release From Host Cell Multivesicular Body Organization Multivesicular Body Assembly Regulation Of Spindle Assembly Vesicle Budding From Membrane Late Endosome To Vacuole Transport Cytokinetic Process Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Nuclear Membrane Organization Autophagosome Maturation Autophagosome Membrane Metaphase Chromosome Alignment Membrane Assembly Lysosomal Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcytosis Alpha-2 Macroglobulin Receptor Activity Apolipoprotein Receptor Activity Type II Interferon Binding Chromosome Localization Endosome Organization	Viral Budding Via Host ESCRT Complex Midbody Abscission Viral Budding Mitotic Cytokinetic Process Multivesicular Body Assembly Viral Budding From Plasma Membrane Multivesicular Body Organization Endosome Organization Cytokinetic Process Mitotic Metaphase Chromosome Alignment Late Endosome To Lysosome Transport Regulation Of Mitotic Spindle Assembly Metaphase Chromosome Alignment Nuclear Membrane Reassembly Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Regulation Of Spindle Assembly Multivesicular Body-lysosome Fusion Chromosome Localization Nuclear Pore Late Endosome To Vacuole Transport Lysosomal Membrane Organization Nucleus Organization Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Sorting Pathway Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Nuclear Membrane Organization Autophagosome Maturation Kinetochore Microtubule Membrane Assembly Viral Process Multivesicular Body Membrane Vesicle Organization Vesicle Budding From Membrane Midbody Vesicle Fusion Organelle Membrane Fusion Multivesicular Body Regulation Of Centrosome Duplication Plasma Membrane Organization Lysosomal Transport Autophagosome Membrane Organelle Fusion Regulation Of Centrosome Cycle