CHMP4B

Description		charged multivesicular body protein 4B
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GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Mitotic Cytokinesis Plasma Membrane Repair Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Viral Budding From Plasma Membrane Nervous System Process Protein Polymerization Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Refractive error ( 32231278) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		18 interacting genes: CEBPA CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PLIN3 PTPN23 SNCA STAMBP UBE2I VPS4A
Entrez ID		128866
HPRD ID		16642
Ensembl ID		ENSG00000101421
Uniprot IDs		Q9H444
PDB IDs		3C3Q 3UM3 4ABM 5MK2
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Midbody Abscission Nuclear Membrane Reassembly Viral Budding Mitotic Cytokinetic Process Viral Budding From Plasma Membrane Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Late Endosome To Lysosome Transport Endosome Transport Via Multivesicular Body Sorting Pathway Mitotic Metaphase Chromosome Alignment Regulation Of Mitotic Spindle Assembly Multivesicular Body Sorting Pathway Nucleus Organization Nuclear Membrane Organization ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Membrane Assembly Metaphase Chromosome Alignment Viral Release From Host Cell Multivesicular Body-lysosome Fusion Plasma Membrane Repair Regulation Of Spindle Assembly Lysosomal Membrane Organization Chromosome Localization Endosome Organization Regulation Of Mitotic Spindle Organization Nuclear Pore Membrane Fission Kinetochore Microtubule Autophagosome Maturation Multivesicular Body Membrane Viral Process Regulation Of Microtubule Cytoskeleton Organization Vacuolar Transport Multivesicular Body Vesicle Fusion Autophagy Organelle Membrane Fusion Autophagosome Membrane Plasma Membrane Organization Lysosomal Transport Endosome Organelle Fusion Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Protein-containing Complex Disassembly
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