ZCCHC12 and SUMO2

Number of citations of the paper that reports this interaction (PMID 16524884)
113

Data Source:
BioGRID (two hybrid)

		ZCCHC12	SUMO2
Gene Name		zinc finger, CCHC domain containing 12	small ubiquitin-like modifier 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Speck	Nucleus Nucleoplasm PML Body
	Molecular Function	Nucleic Acid Binding Zinc Ion Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	Protein Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated BMP Signaling Pathway	Protein Sumoylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP APPBP2 MAGEA11 PNMA1 SUMO1 SUMO2 TFCP2	91 interactors: ALAS1 ARL13A ARNTL ATXN1 ATXN7 AURKB BAD BCL11A BLM BRCC3 BRE C18orf25 CCNE2 CDCA8 CENPC CHAF1A CHD3 CMTM6 CORO2A CSNK2B CUL3 FAM175A FOS HDAC4 HDAC9 HIF1A HIPK2 HNF4A HOMEZ HSF2 JUN KALRN KDM1A KRT14 KRT5 KRT8 LEF1 MAF1 MAST2 MDC1 MSX1 MYB NFKBIA PARP1 PIAS1 PIAS2 PIAS3 PIAS4 PML RAC1 RANGAP1 RB1 RNF111 RNF4 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SH3KBP1 SLC22A2 SNCA SOX10 SOX6 SP100 STK24 SUMO1 TDG TDP2 TEAD3 TNIP1 TOPORS TP53BP2 TRIM63 UBA2 UBE2I USP25 USPL1 VIM WRN XPC ZBTB1 ZCCHC12 ZCCHC7 ZHX1 ZMYM2 ZMYM5
Entrez ID		170261	6613
HPRD ID		06616	04332
Ensembl ID		ENSG00000174460	ENSG00000188612
Uniprot IDs		Q6PEW1	P61956
PDB IDs			1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2RPQ 3UIN 3UIO
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Synaptic Growth At Neuromuscular Junction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Collateral Sprouting In Absence Of Injury PML Body Organization Regulation Of Proteasomal Protein Catabolic Process Post-translational Protein Modification Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Protein Catabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Localization To Nuclear Pore Axon Choice Point Recognition Protein Localization To Nuclear Envelope Peptidyl-lysine Modification Regulation Of Binding Positive Regulation Of Cellular Protein Metabolic Process Neuron Remodeling Positive Regulation Of Protein Metabolic Process Immune Response Defense Response Regulation Of Protein Catabolic Process Cellular Copper Ion Homeostasis Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Copper Ion Homeostasis Suckling Behavior	Protein Sumoylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Peptidyl-lysine Modification Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Binding RNA Metabolic Process Cellular Metabolic Process Gene Expression Chromosome Organization Organelle Organization Regulation Of DNA Binding Biosynthetic Process Response To Stimulus Regulation Of Cellular Process Cellular Response To Stimulus Negative Regulation Of Binding Protein Modification By Small Protein Conjugation Peptidyl-amino Acid Modification Regulation Of Cell Differentiation Regulation Of Signal Transduction Cellular Response To Stress
Tagcloud ?			augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief rev1 sensing short specialized starvation suppressor therapies toxic turn
Tagcloud (Difference) ?			augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief rev1 sensing short specialized starvation suppressor therapies toxic turn
Tagcloud (Intersection) ?