CRB3 and MPP5

Number of citations of the paper that reports this interaction (PMID 12771187)
42

Data Source:
HPRD (in vivo, in vitro)

		CRB3	MPP5
Gene Name		crumbs family member 3	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Tight Junction Integral Component Of Membrane Apical Plasma Membrane Cell Junction Protein Complex Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Plasma Membrane Tight Junction Endomembrane System Myelin Sheath Adaxonal Region Lateral Loop Schmidt-Lanterman Incisure Protein Complex Extracellular Vesicular Exosome
	Molecular Function	SH3 Domain Binding Protein Domain Specific Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Cell Junction Assembly Cell-cell Junction Organization Tight Junction Assembly Protein Localization To Plasma Membrane	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Cell Junction Assembly Protein Localization To Myelin Sheath Abaxonal Region Cell-cell Junction Organization Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions	Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: INADL MPP5 PARD6A PSMA3 WDR83	6 interactors: ARF6 CRB3 INADL LIN7A MPP4 PARD6B
Entrez ID		92359	64398
HPRD ID		16749	09508
Ensembl ID		ENSG00000130545	ENSG00000072415
Uniprot IDs		Q9BUF7	Q658X5 Q8N3R9
PDB IDs			1Y76 3UIT
Enriched GO Terms of Interacting Partners?		Tight Junction Assembly Apical Junction Assembly Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Junction Organization Protein Localization To Myelin Sheath Abaxonal Region	Tight Junction Assembly Apical Junction Assembly Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Protein Localization Protein Localization To Plasma Membrane Protein Localization To Basolateral Plasma Membrane Plasma Membrane Organization Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Myeloid Cell Apoptotic Process Protein Localization To Endosome Maintenance Of Cell Polarity Cellular Protein Localization Protein Localization To Membrane Establishment Of Epithelial Cell Polarity Cell Division Endomembrane System Organization Protein Localization To Cell Surface Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Hepatocyte Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Ruffle Organization Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Endocytosis Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Regulation Of Protein Localization To Plasma Membrane
Tagcloud ?		asymmetry complex conserved crumbs defective dysregulation epithelium fate focus homolog invasion kidney mainly mammary member migration mouse numerous organelle par partitioning polarity roles scrib scribble shape suppressor transport	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Difference) ?		asymmetry complex conserved crumbs defective dysregulation epithelium fate focus homolog invasion kidney mainly mammary member migration mouse numerous organelle par partitioning polarity roles scrib scribble shape suppressor transport	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Intersection) ?