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CRB3
Description
crumbs cell polarity complex component 3
Image
GO Annotations
Cellular Component
Plasma Membrane
Bicellular Tight Junction
Membrane
Apical Plasma Membrane
Cell Junction
Protein-containing Complex
Subapical Complex
Apical Junction Complex
Apical Part Of Cell
Extracellular Exosome
Anchoring Junction
Molecular Function
Protein Binding
SH3 Domain Binding
Protein Domain Specific Binding
Biological Process
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Protein Localization To Plasma Membrane
Positive Regulation Of Cell Junction Assembly
Pathways
Tight junction interactions
SARS-CoV-2 targets PDZ proteins in cell-cell junction
Drugs
Diseases
GWAS
Interacting Genes
28 interacting genes:
ANKRD46
BCL2L13
BET1
FUNDC2
HMOX1
HMOX2
NDUFA3
PALS1
PARD6A
PATJ
PLLP
PLP2
PSENEN
PSMA3
RABAC1
SERF1A
SERF1B
SERP1
SLC39A9
STX5
TECR
TMEM222
TREX1
UBIAD1
VAMP1
VTI1B
WDR83
YIPF6
Entrez ID
92359
HPRD ID
16749
Ensembl ID
ENSG00000130545
Uniprot IDs
Q9BUF7
PDB IDs
5I7Z
Enriched GO Terms of Interacting Partners
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Endoplasmic Reticulum Membrane
SNAP Receptor Activity
Membrane
SNARE Complex
Heme Oxidation
Heme Oxygenase (decyclizing) Activity
Vesicle Fusion
Organelle Membrane Fusion
Golgi Apparatus
Endomembrane System
Organelle Fusion
Vesicle Fusion With Golgi Apparatus
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Endoplasmic Reticulum
Establishment Or Maintenance Of Apical/basal Cell Polarity
Heme Catabolic Process
Membrane Fusion
Porphyrin-containing Compound Catabolic Process
Myelin Assembly
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Membrane Organization
Golgi Organization
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Golgi Vesicle Transport
Amyloid Fibril Formation
Apical Junction Complex
Bicellular Tight Junction
Protein Binding
Autophagy
Heme Metabolic Process
Vesicle Organization
Immune Complex Formation
Adenyl Deoxyribonucleotide Binding
Immune Response In Brain Or Nervous System
Vitamin K Biosynthetic Process
Menaquinone Biosynthetic Process
Protein Localization To Myelin Sheath Abaxonal Region
Tight Junction
Porphyrin-containing Compound Metabolic Process
Macroautophagy
Establishment Or Maintenance Of Cell Polarity
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