MPP5 and LIN7A

Number of citations of the paper that reports this interaction (PMID 10753959)
40

Data Source:
HPRD (in vitro)

		MPP5	LIN7A
Gene Name		membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	lin-7 homolog A (C. elegans)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Tight Junction Endomembrane System Myelin Sheath Adaxonal Region Lateral Loop Schmidt-Lanterman Incisure Protein Complex Extracellular Vesicular Exosome	Cell-cell Junction Tight Junction Postsynaptic Density Basolateral Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane Extracellular Vesicular Exosome MPP7-DLG1-LIN7 Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Cell Junction Assembly Protein Localization To Myelin Sheath Abaxonal Region Cell-cell Junction Organization Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane	Protein Complex Assembly Exocytosis Neurotransmitter Secretion Asymmetric Protein Localization Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein Localization To Basolateral Plasma Membrane
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS			Dental caries ( 23259602)
Protein-Protein Interactions		6 interactors: ARF6 CRB3 INADL LIN7A MPP4 PARD6B	19 interactors: ABCA1 APP BAI1 BAIAP2 CASK DLG2 DLG3 DLG4 FAM9B GOLGA2 GRIN2B KCNJ12 MPP2 MPP3 MPP5 MPP6 NOTCH2NL SLC6A12 ZYX
Entrez ID		64398	8825
HPRD ID		09508	04542
Ensembl ID		ENSG00000072415	ENSG00000111052
Uniprot IDs		Q658X5 Q8N3R9	O14910
PDB IDs		1Y76 3UIT
Enriched GO Terms of Interacting Partners?		Tight Junction Assembly Apical Junction Assembly Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Protein Localization Protein Localization To Plasma Membrane Protein Localization To Basolateral Plasma Membrane Plasma Membrane Organization Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Myeloid Cell Apoptotic Process Protein Localization To Endosome Maintenance Of Cell Polarity Cellular Protein Localization Protein Localization To Membrane Establishment Of Epithelial Cell Polarity Cell Division Endomembrane System Organization Protein Localization To Cell Surface Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Hepatocyte Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Ruffle Organization Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Endocytosis Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Regulation Of Protein Localization To Plasma Membrane	Nucleotide Phosphorylation Receptor Localization To Synapse Protein Localization To Synapse Axonogenesis Signaling Cell-cell Signaling Cell Communication Nucleotide Metabolic Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Neuron Projection Morphogenesis Nucleobase-containing Small Molecule Metabolic Process Receptor Clustering Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Membrane Organization Cell Part Morphogenesis Cellular Component Assembly Neuron Development Signal Transduction Organophosphate Metabolic Process Secretion Cell Morphogenesis Cellular Response To Stimulus Neuron Differentiation Neurogenesis Neuromuscular Process Nervous System Development Suckling Behavior Cell Projection Organization Protein Localization To Membrane Dendrite Development Multicellular Organismal Development Small Molecule Metabolic Process Learning Axon Guidance Anatomical Structure Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Cell Development Regulation Of Synaptic Plasticity Phosphorylation System Development Cell Differentiation Secretion By Cell Ionotropic Glutamate Receptor Signaling Pathway Developmental Process Generation Of Neurons Protein Localization To Myelin Sheath Abaxonal Region
Tagcloud ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1	adherens associates cadherin carboxyl changing compartment deleted dimer dimerizes dlg1 guanylate homology insoluble junctions l27 lin7c localizes maguk members mpp7 pdz redistributes requiring stabilizes stabilizing stardust tripartite uncharacterized
Tagcloud (Difference) ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1	adherens associates cadherin carboxyl changing compartment deleted dimer dimerizes dlg1 guanylate homology insoluble junctions l27 lin7c localizes maguk members mpp7 pdz redistributes requiring stabilizes stabilizing stardust tripartite uncharacterized
Tagcloud (Intersection) ?