MPP5 and MPP4

Number of citations of the paper that reports this interaction (PMID 15914641)
14

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MPP5	MPP4
Gene Name		membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Tight Junction Endomembrane System Myelin Sheath Adaxonal Region Lateral Loop Schmidt-Lanterman Incisure Protein Complex Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Presynaptic Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Domain Specific Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Cell Junction Assembly Protein Localization To Myelin Sheath Abaxonal Region Cell-cell Junction Organization Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane	Protein Localization To Synapse
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ARF6 CRB3 INADL LIN7A MPP4 PARD6B	2 interactors: FASLG MPP5
Entrez ID		64398	58538
HPRD ID		09508	07360
Ensembl ID		ENSG00000072415	ENSG00000082126
Uniprot IDs		Q658X5 Q8N3R9	E7ET46 E9PG92 F6Q0Y6 Q96JB8
PDB IDs		1Y76 3UIT
Enriched GO Terms of Interacting Partners?		Tight Junction Assembly Apical Junction Assembly Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Protein Localization Protein Localization To Plasma Membrane Protein Localization To Basolateral Plasma Membrane Plasma Membrane Organization Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Myeloid Cell Apoptotic Process Protein Localization To Endosome Maintenance Of Cell Polarity Cellular Protein Localization Protein Localization To Membrane Establishment Of Epithelial Cell Polarity Cell Division Endomembrane System Organization Protein Localization To Cell Surface Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Hepatocyte Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Ruffle Organization Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Endocytosis Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Regulation Of Protein Localization To Plasma Membrane	Protein Localization To Myelin Sheath Abaxonal Region Endosomal Lumen Acidification Retinal Cell Programmed Cell Death Endomembrane System Organization Necroptotic Signaling Pathway Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Chloride Ion Homeostasis Positive Regulation Of Endothelial Cell Apoptotic Process T Cell Apoptotic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular PH Reduction Peripheral Nervous System Myelin Maintenance PH Reduction Positive Regulation Of ERBB Signaling Pathway Asymmetric Protein Localization Endosome Organization Myelin Assembly Necroptotic Process Myelin Maintenance Regulation Of Endothelial Cell Apoptotic Process Developmental Programmed Cell Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Intracellular PH Programmed Necrotic Cell Death Anion Homeostasis Myelination In Peripheral Nervous System Regulation Of Cellular PH Necrotic Cell Death Tight Junction Assembly Schwann Cell Development Positive Regulation Of Neuron Apoptotic Process Morphogenesis Of An Epithelial Sheet Schwann Cell Differentiation Cell Development Regulation Of PH Apical Junction Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death Establishment Of Protein Localization To Plasma Membrane Regulation Of ERBB Signaling Pathway Negative Regulation Of Angiogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Glial Cell Development Extrinsic Apoptotic Signaling Pathway Zymogen Activation Peripheral Nervous System Development Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Tagcloud ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1	adherens colocalized crb1 crumbs dlg1 glia guanylate implicate junctions mpp3 mpp5 muller olm organize outer palmitoylated photoreceptor pigmentosa pinpoint plexiform polarity retina retinae retinitis retinopathies scaffold subapical synapse unrecognized
Tagcloud (Difference) ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1	adherens colocalized crb1 crumbs dlg1 glia guanylate implicate junctions mpp3 muller olm organize outer palmitoylated photoreceptor pigmentosa pinpoint plexiform polarity retina retinae retinitis retinopathies scaffold subapical synapse unrecognized
Tagcloud (Intersection) ?		mpp5