CRB3 and SERF1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CRB3	SERF1B
Description		crumbs cell polarity complex component 3	small EDRK-rich factor 1B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Subapical Complex Apical Junction Complex Apical Part Of Cell Extracellular Exosome Anchoring Junction	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Plasma Membrane Positive Regulation Of Cell Junction Assembly	Nervous System Development Protein Destabilization Amyloid Fibril Formation
Pathways		Tight junction interactions SARS-CoV-2 targets PDZ proteins in cell-cell junction
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: ANKRD46 BCL2L13 BET1 FUNDC2 HMOX1 HMOX2 NDUFA3 PALS1 PARD6A PATJ PLLP PLP2 PSENEN PSMA3 RABAC1 SERF1A SERF1B SERP1 SLC39A9 STX5 TECR TMEM222 TREX1 UBIAD1 VAMP1 VTI1B WDR83 YIPF6	12 interacting genes: ABHD16A AQP6 CERS4 CRB3 ELOVL4 ELOVL7 GPR152 REEP4 RNASEK TIMMDC1 TMEM14B TMX2
Entrez ID		92359	728492
HPRD ID		16749
Ensembl ID		ENSG00000130545	ENSG00000205572
Uniprot IDs		Q9BUF7	O75920
PDB IDs		5I7Z
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane SNAP Receptor Activity Membrane SNARE Complex Heme Oxidation Heme Oxygenase (decyclizing) Activity Vesicle Fusion Organelle Membrane Fusion Golgi Apparatus Endomembrane System Organelle Fusion Vesicle Fusion With Golgi Apparatus Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Endoplasmic Reticulum Establishment Or Maintenance Of Apical/basal Cell Polarity Heme Catabolic Process Membrane Fusion Porphyrin-containing Compound Catabolic Process Myelin Assembly Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Membrane Organization Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Amyloid Fibril Formation Apical Junction Complex Bicellular Tight Junction Protein Binding Autophagy Heme Metabolic Process Vesicle Organization Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Protein Localization To Myelin Sheath Abaxonal Region Tight Junction Porphyrin-containing Compound Metabolic Process Macroautophagy Establishment Or Maintenance Of Cell Polarity	Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Membrane Fatty Acid Derivative Metabolic Process Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Sphingolipid Biosynthetic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Amide Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Sphingolipid Metabolic Process Fatty-acyl-CoA Biosynthetic Process Mitochondrial Membrane Very Long-chain Fatty Acid Metabolic Process Membrane Lipid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Endoplasmic Reticulum Membrane Fatty Acid Derivative Biosynthetic Process Nitrate Transmembrane Transporter Activity PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Acyl-CoA Metabolic Process Unsaturated Fatty Acid Metabolic Process Sulfur Compound Biosynthetic Process Subapical Complex Endoplasmic Reticulum Fatty Acid Biosynthetic Process Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Monoacylglycerol Catabolic Process Sphingosine N-acyltransferase Activity Lipid Metabolic Process Lipid Biosynthetic Process Monoatomic Anion Channel Activity Renal Water Transport Ammonium Channel Activity Disulfide Oxidoreductase Activity Ammonium Transmembrane Transport Mitotic Nuclear Membrane Reassembly Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain G Protein-coupled Photoreceptor Activity Monoacylglycerol Lipase Activity Receptor-mediated Endocytosis Of Virus By Host Cell Water Channel Activity Endosomal Lumen Acidification
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