TMEM88 and NKG7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM88	NKG7
Description		transmembrane protein 88	natural killer cell granule protein 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane	Lysosome Plasma Membrane Membrane Cytolytic Granule Cytolytic Granule Membrane
	Molecular Function	Protein Binding PDZ Domain Binding	Protein Binding
	Biological Process	Wnt Signaling Pathway Protein Stabilization Protein Localization To Plasma Membrane Negative Regulation Of Canonical Wnt Signaling Pathway	Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Inflammatory Response Killing Of Cells Of Another Organism CD4-positive, Alpha-beta T Cell Activation Natural Killer Cell Mediated Cytotoxicity Defense Response To Protozoan Natural Killer Cell Degranulation Positive Regulation Of Inflammatory Response Granzyme-mediated Programmed Cell Death Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		9 interacting genes: GYPC MFF NKG7 TIMM23 TMEM11 TMEM218 TMEM50B VRK2 ZDHHC22	49 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM209A FAM210B FFAR2 FKBP7 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC10A1 SLC18A2 SLC30A8 SLC35H1 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88
Entrez ID		92162	4818
HPRD ID		17438	16188
Ensembl ID		ENSG00000167874	ENSG00000105374
Uniprot IDs		I3L2J3 Q6PEY1	A0A0B4J2A6 Q16617
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Targeting Protein Targeting To Mitochondrion Membrane Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Organelle Envelope Establishment Of Protein Localization To Mitochondrion	Membrane Plasma Membrane Protein Binding
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