NKG7 and RNF24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NKG7	RNF24
Description		natural killer cell granule protein 7	ring finger protein 24
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Membrane Cytolytic Granule Cytolytic Granule Membrane	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Inflammatory Response Killing Of Cells Of Another Organism CD4-positive, Alpha-beta T Cell Activation Natural Killer Cell Mediated Cytotoxicity Defense Response To Protozoan Natural Killer Cell Degranulation Positive Regulation Of Inflammatory Response Granzyme-mediated Programmed Cell Death Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Nevirapine-induced hypersensitivity in HIV (drug-induced liver injury) ( 28062682) PR interval ( 32439900) Response to antidepressants in depression ( 27622933) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		49 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM209A FAM210B FFAR2 FKBP7 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC10A1 SLC18A2 SLC30A8 SLC35H1 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	17 interacting genes: ABHD5 ARMC1 BNIP3 CNIH1 GOLT1A LHFPL3 NKG7 NRSN1 NT5E PLP1 SLC10A6 SLC71A2 TIMMDC1 TMX2 TRPC6 UQCRH VAMP1
Entrez ID		4818	11237
HPRD ID		16188	10198
Ensembl ID		ENSG00000105374	ENSG00000101236
Uniprot IDs		A0A0B4J2A6 Q16617	Q9Y225
PDB IDs			2EP4
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding	Membrane Granzyme-mediated Programmed Cell Death Signaling Pathway
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