NKG7 and CLSTN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NKG7	CLSTN3
Description		natural killer cell granule protein 7	calsyntenin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Membrane Cytolytic Granule Cytolytic Granule Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Cell Surface Postsynaptic Density Membrane Dendrite Protein-containing Complex Cell Projection Organelle Membrane Contact Site Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Neurexin Family Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Inflammatory Response Killing Of Cells Of Another Organism CD4-positive, Alpha-beta T Cell Activation Natural Killer Cell Mediated Cytotoxicity Defense Response To Protozoan Natural Killer Cell Degranulation Positive Regulation Of Inflammatory Response Granzyme-mediated Programmed Cell Death Signaling Pathway	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Protein Secretion Negative Regulation Of Lipid Storage L-ascorbic Acid Metabolic Process Synaptic Transmission, Glutamatergic Positive Regulation Of Synaptic Transmission Positive Regulation Of Lipid Catabolic Process Synaptic Transmission, GABAergic Regulation Of Synapse Assembly Positive Regulation Of Synapse Assembly Sympathetic Neuron Projection Extension Cell-cell Adhesion Cold-induced Thermogenesis Lipid Droplet Fusion Negative Regulation Of Lipid Droplet Fusion Positive Regulation Of Protein Localization To Synapse Excitatory Synapse Assembly Inhibitory Synapse Assembly Regulation Of Excitatory Synapse Assembly Negative Regulation Of Excitatory Synapse Assembly Regulation Of Presynapse Assembly Positive Regulation Of Inhibitory Synapse Assembly Adaptive Thermogenesis
Pathways
Drugs
Diseases
GWAS		Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494)	Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Schizophrenia ( 30285260)
Interacting Genes		49 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM209A FAM210B FFAR2 FKBP7 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC10A1 SLC18A2 SLC30A8 SLC35H1 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	12 interacting genes: APBA2 CMTM7 MAL NKG7 OLFM4 PGAP2 RSPH1 TMEM107 TMEM54 TMEM97 TRAM1L1 ZDHHC22
Entrez ID		4818	9746
HPRD ID		16188	16725
Ensembl ID		ENSG00000105374	ENSG00000139182
Uniprot IDs		A0A0B4J2A6 Q16617	Q9BQT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding
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